The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

Atherosclerosis, the chronic accumulation of cholesterol-rich plaque within arteries, is
associated with a broad spectrum of cardiovascular diseases including myocardial …

Recent genome-wide association and transcriptome-wide association studies have
identified an association between the PALMD locus, encoding palmdelphin, a protein …

Background The dynamics of the cellular glycolysis pathway underpin cellular function and
dysfunction, and therefore ultimately health, disease, diagnostic and therapeutic strategies …

The physiological functions of endothelial cells control vascular tone, permeability,
inflammation, and angiogenesis, which significantly help to maintain a healthy vascular …

Atherosclerosis is a chronic inflammatory vascular disease associated with endothelial
dysfunction, inflammation, and atherosclerotic plaque formation. Glycolysis is a conservative …

Glycometabolism is well known for its roles as the main source of energy, which mainly
includes three metabolic pathways: oxidative phosphorylation, glycolysis and pentose …

Background and aims Metabolic reprogramming of innate immune cells is emerging as a
key player in the progression of a number of chronic diseases, including atherosclerosis …

NR2F2 is expressed in endothelial cells (ECs) and Nr2f2 knockout produces lethal
cardiovascular defects. In humans, reduced NR2F2 expression is associated with …

Atherosclerosis is commonly known as an inflammatory disease that is characterized by lipid
deposition in the arterial wall, causing gradual restriction or complete blockade of blood …