Coronary artery disease (CAD) and its complications are the leading cause of death
worldwide. Inflammatory activation and dysfunction of the endothelium are key events in the …

The vascular endothelium, a monolayer of endothelial cells (EC), constitutes the inner
cellular lining of arteries, veins and capillaries and therefore is in direct contact with the …

The vascular endothelial surface is coated by the glycocalyx, a ubiquitous gel‐like layer
composed of a membrane‐binding domain that contains proteoglycans, glycosaminoglycan …

Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …

The endothelial glycocalyx has a profound influence at the vascular wall on the transmission
of shear stress, on the maintenance of a selective permeability barrier and a low hydraulic …

The endothelial glycocalyx is an important part of the vascular barrier. The glycocalyx is
intimately linked to the homoeostatic functions of the endothelium. Damage to the glycocalyx …

The vascular endothelial glycocalyx is a dense, bush-like structure that is synthesized and
secreted by endothelial cells and evenly distributed on the surface of vascular endothelial …

Methods This was a substudy of a multicenter trial in which nonbleeding critically ill patients
with an increased International Normalized Ratio (1.5 to 3.0) were randomized to omitting or …

The glycocalyx of the endothelium is an intravascular compartment that creates a barrier
between circulating blood and the vessel wall. The glycocalyx is suggested to play an …

The endothelium holds a pivotal role in cardiovascular health and disease. Assessment of
its function was until recently limited to experimental designs due to its location. The advent …