Duality of interactions between TGF-β and TNF-α during tumor formation

Z Liu, Y Zhang, L Zhang, T Zhou, Y Li, G Zhou… - Frontiers in …, 2022 - frontiersin.org
The tumor microenvironment is essential for the formation and development of tumors.
Cytokines in the microenvironment may affect the growth, metastasis and prognosis of …

Molecular pathways governing the termination of liver regeneration

LR de Haan, RF van Golen, M Heger, M Michel - Pharmacological reviews, 2024 - Elsevier
The liver has the unique capacity to regenerate, and up to 70% of the liver can be removed
without detrimental consequences to the organism. Liver regeneration is a complex process …

Hepatopulmonary syndrome is associated with low sphingosine-1-phosphate levels and can be ameliorated by the functional agonist fingolimod

S Baweja, A Kumari, P Negi, A Tomar, DM Tripathi… - Journal of …, 2023 - Elsevier
Background & Aims Hepatopulmonary syndrome (HPS) is characterised by a defect in
arterial oxygenation induced by pulmonary vascular dilatation in patients with liver disease …

CXCR2 is involved in pulmonary intravascular macrophage accumulation and angiogenesis in a rat model of hepatopulmonary syndrome

X Li, Y Chen, Y Chang, S Li, Z Zhao, H Zhang - Clinical Science, 2017 - portlandpress.com
Hepatopulmonary syndrome (HPS) is a lung complication in various liver diseases, with
high incidence, poor prognosis and no effective non-surgical treatments in patients with …

Reno-protective effect of nicorandil and pentoxifylline against potassium dichromate-induced acute renal injury via modulation p38MAPK/Nrf2/HO-1 and Notch1/TLR4 …

EAM El-Shoura, LA Abdelzaher, AAN Ahmed… - Journal of Trace …, 2024 - Elsevier
Background Occupational and environmental exposure to chromium compounds such as
potassium dichromate (PDC)(K 2 Cr 2 O 7) has emerged as a potential aetiologic cause for …

circRNA‐14723 promotes hepatocytes proliferation in rat liver regeneration by sponging rno‐miR‐16‐5p

X Guo, L Xi, L Li, J Guo, W Jin, C Chang… - Journal of cellular …, 2020 - Wiley Online Library
Circular RNA (circRNA) is a subclass of noncoding RNA (ncRNA) detected within
mammalian tissues and cells. However, its regulatory role during the proliferation phase of …

Pentoxifylline prevents driamycin-induced myocardial fibrosis and apoptosis in rats

Z Zang, S Li, Y Lin, X Li, Y Li, Y Qin, H Wang… - International Heart …, 2015 - jstage.jst.go.jp
Adriamycin (ADR) is a potent antineoplastic agent, but long-term treatment is limited by its
cumulative, life-threatening cardiomyopathy. Recently, a few reports have shown that …

Unveiling the power of microenvironment in liver regeneration: an in-depth overview

Y Hu, R Wang, N An, C Li, Q Wang, Y Cao, C Li… - Frontiers in …, 2023 - frontiersin.org
The liver serves as a vital regulatory hub for various physiological processes, including
sugar, protein, and fat metabolism, coagulation regulation, immune system maintenance …

[HTML][HTML] Development of a rat model of D-galactosamine/lipopolysaccharide induced hepatorenal syndrome

JB Wang, HT Wang, LP Li, YC Yan… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To develop a practical and reproducible rat model of hepatorenal syndrome for further
study of the pathophysiology of human hepatorenal syndrome. METHODS: Sprague-Dawley …

The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of d-galactosamine-induced acute hepatitis in rats

E Taslidere, N Vardi, M Esrefoglu… - Human & …, 2016 - journals.sagepub.com
The aim of this study was to investigate histological changes in hepatic tissue and effects of
pentoxifylline (PTX) and caffeic acid phenethyl ester (CAPE) on these changes using …