The contribution of microglia and brain-infiltrating macrophages to the pathogenesis of neuroinflammatory and neurodegenerative diseases during TMEV infection of …
AB DePaula-Silva - Viruses, 2024 - mdpi.com
The infection of the central nervous system (CNS) with neurotropic viruses induces
neuroinflammation and is associated with the development of neuroinflammatory and …
neuroinflammation and is associated with the development of neuroinflammatory and …
An appraisal of emerging therapeutic targets for multiple sclerosis derived from current preclinical models
Introduction Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and
neurodegenerative condition affecting the central nervous system (CNS). Although …
neurodegenerative condition affecting the central nervous system (CNS). Although …
IFNAR signaling of neuroectodermal cells is essential for the survival of C57BL/6 mice infected with Theiler's murine encephalomyelitis virus
M Bühler, D Li, L Li, S Runft, I Waltl, A Pavlou… - Journal of …, 2023 - Springer
Background Theiler's murine encephalomyelitis virus (TMEV) is a single-stranded RNA virus
that causes encephalitis followed by chronic demyelination in SJL mice and spontaneous …
that causes encephalitis followed by chronic demyelination in SJL mice and spontaneous …
Chronic encephalomyelitis virus exhibits cellular tropism and evades pDCs by binding to sialylated integrins as the cell surface receptors
K Takeda, T Kaifu, R Michihata… - European Journal of …, 2023 - Wiley Online Library
Theiler's murine encephalomyelitis virus (TMEV) causes a chronic demyelinating disease
similar to multiple sclerosis in mice. Although sialic acids have been shown to be essential …
similar to multiple sclerosis in mice. Although sialic acids have been shown to be essential …
ASC-and caspase-1-deficient C57BL/6 mice do not develop demyelinating disease after infection with Theiler's murine encephalomyelitis virus
D Li, M Bühler, S Runft, G Gerold, K Marek… - Scientific reports, 2023 - nature.com
Theiler's murine encephalomyelitis virus (TMEV) induces an acute polioencephalomyelitis
and a chronic demyelinating leukomyelitis in SJL mice. C57BL/6 (B6) mice generally do not …
and a chronic demyelinating leukomyelitis in SJL mice. C57BL/6 (B6) mice generally do not …
Theiler's Murine Encephalomyelitis Virus Replicates in Primary Neuron Cultures and Impairs Spine Density Formation
C Tomatis, A León, AOL Ortiz, P Oneto, F Fuentes… - Neuroscience, 2023 - Elsevier
In this study, we examined infection with the highly neurovirulent GDVII, the less
neurovirulent DA strains, and with a mutant DA, which lacks the L* protein (L*-1) involved in …
neurovirulent DA strains, and with a mutant DA, which lacks the L* protein (L*-1) involved in …
Application of Theiler's murine encephalomyelitis virus in treatment of multiple sclerosis
L Li, R Zhou, L Sun - Frontiers in Microbiology, 2024 - frontiersin.org
Theiler's murine encephalomyelitis virus (TMEV) infected mice have been often used as an
animal model for Multiple sclerosis (MS) due to their similar pathology in the central nervous …
animal model for Multiple sclerosis (MS) due to their similar pathology in the central nervous …