The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease

A Garcia, O Grundmann - Mini Reviews in Medicinal Chemistry, 2024 - ingentaconnect.com
Alongside the prescription of commonly used antivirals, such as acyclovir, remdesivir,
oseltamivir, and ciprofloxacin, the most efficient way to prevent or treat communicable …

[PDF][PDF] Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26. ZEBOV/MVA-BN-Filo

F Blengio, H Hocini, L Richert, C Lefebvre, M Durand… - Cell Reports, 2023 - cell.com
Ebola virus disease is a severe hemorrhagic fever with a high fatality rate. We investigate
transcriptome profiles at 3 h, 1 day, and 7 days after vaccination with Ad26. ZEBOV and MVA …

[HTML][HTML] Baseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts

PC Gonzalez Dias Carvalho… - Frontiers in …, 2023 - frontiersin.org
Introduction The rVSVDG-ZEBOV-GP (Ervebo®) vaccine is both immunogenic and
protective against Ebola. However, the vaccine can cause a broad range of transient …

[HTML][HTML] Whole blood RNA signatures in tuberculosis patients receiving H56: IC31 vaccine as adjunctive therapy

N Alonso-Rodríguez, E Vianello, S van Veen… - Frontiers in …, 2024 - frontiersin.org
Introduction Therapeutic vaccination in tuberculosis (TB) represents a Host Directed
Therapy strategy which enhances immune responses in order to improve clinical outcomes …

[HTML][HTML] Refined innate plasma signature after rVSVΔG-ZEBOV-GP immunization is shared among adult cohorts in Europe and North America

PA Martinez-Murillo, A Huttner, S Lemeille… - Frontiers in …, 2024 - frontiersin.org
Background During the last decade Ebola virus has caused several outbreaks in Africa. The
recombinant vesicular stomatitis virus-vectored Zaire Ebola (rVSVΔG-ZEBOV-GP) vaccine …

[PDF][PDF] Global blood miRNA profiling unravels early signatures of immunogenicity of Ebola vaccine rVSVΔG-ZEBOV-GP

E Vianello, J Persson, B Andersson, S van Veen… - iScience, 2023 - cell.com
The vectored Ebola vaccine rVSVΔG-ZEBOV-GP elicits protection against Ebola Virus
Disease (EVD). In a study of forty-eight healthy adult volunteers who received either the …

[PDF][PDF] Huttner

P Martinez-Murillo - Lemeille, S., Medaglini, D …, 2024 - scholarlypublications …
Background: During the last decade Ebola virus has caused several outbreaks in Africa. The
recombinant vesicular stomatitis virus-vectored Zaire Ebola (rVSV∆ GZEBOV-GP) vaccine …