Controlling the causative agents of coccidiosis in domestic chickens; an eye on the past and considerations for the future

E Attree, G Sanchez-Arsuaga, M Jones, D Xia… - CABI Agriculture and …, 2021 - Springer
Coccidiosis is a potentially severe enteritis caused by species of obligate intracellular
parasites of the genus Eimeria. These parasites cause significant economic losses to the …

[HTML][HTML] Recombinant anticoccidial vaccines-a cup half full?

DP Blake, I Pastor-Fernández, MJ Nolan… - Infection, Genetics and …, 2017 - Elsevier
Eimeria species parasites can cause the disease coccidiosis, most notably in chickens. The
occurrence of coccidiosis is currently controlled through a combination of good husbandry …

Toxoplasma gondii vaccine candidates: a concise review

AJ Mamaghani, A Fathollahi, Z Arab-Mazar… - Irish Journal of Medical …, 2023 - Springer
Toxoplasma gondii is an obligate intracellular parasite that causes toxoplasmosis. It has
been shown that the severity of symptoms depends on the functioning of the host immune …

Do Toxoplasma gondii apicoplast proteins have antigenic potential? An in silico study

H Can, SE Alak, AE Köseoğlu, M Döşkaya… - … Biology and Chemistry, 2020 - Elsevier
Toxoplasma gondii, one of the extensively studied Apicomplexan parasites, is prevalent
worldwide in animals and humans. Apart from its nuclear genome, T. gondii contains an …

Vaccination challenges and strategies against long-lived Toxoplasma gondii

FK Loh, S Nathan, SC Chow, CM Fang - Vaccine, 2019 - Elsevier
Since the discovery of Toxoplasma gondii in 1908, it is estimated that one-third of the global
population has been exposed to this ubiquitous intracellular protozoan. The complex life …

GRA8 DNA vaccine formulations protect against chronic toxoplasmosis

M Karakavuk, H Can, A Gül, AD Döşkaya, SE Alak… - Microbial …, 2021 - Elsevier
Toxoplasma gondii has a very wide host range and infects all warm-blooded animals
including humans. The disease causes great economic losses both in animals and humans …

Immunogenicity and protection efficacy of a COVID-19 DNA vaccine encoding spike protein with D614G mutation and optimization of large-scale DNA vaccine …

A Gül, S Erkunt Alak, H Can, M Karakavuk… - Scientific Reports, 2024 - nature.com
Severe acute respiratory syndrome coronavirus 2 had devastating consequences for human
health. Despite the introduction of several vaccines, COVID-19 continues to pose a serious …

Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with …

M Döşkaya, L Liang, A Jain, H Can, S Gülçe İz… - Parasites & vectors, 2018 - Springer
Background Toxoplasma gondii is an obligate intracellular protozoan parasite that causes
congenital toxoplasmosis, as well as other serious clinical presentations in immune …

Development of multistage recombinant protein vaccine formulations against toxoplasmosis using a new chitosan and porin based adjuvant system

S Parmaksız, A Gül, SE Alak, M Karakavuk… - International Journal of …, 2022 - Elsevier
Toxoplasmosis is a global health problem affecting both human and animal populations.
The lack of effective treatment makes the development of a vaccine against toxoplasmosis …

An In house ELISA using recombinant GRA1 and BAG1 proteins as antigen successfully detected Toxoplasma gondii infection in a flock of sheep suffering from …

Ç Kandemir, H Can, M Karakavuk, M Döşkaya… - Research in Veterinary …, 2023 - Elsevier
Toxoplasma gondii is one of the main pathogens causing abortion in sheep. In this study, an
in house ELISA using recombinant GRA1 and BAG1 proteins as antigen was used to detect …