In this review we compare and discuss results of compounds already reported as anticancer
agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds …

Isatin, chemically an indole-1 H-2, 3-dione, is recognised as one of the most attractive
therapeutic fragments in drug design and development. The template has turned out to be …

The strategy of utilizing nitrogen compounds in various biological applications has recently
emerged as a powerful approach to exploring novel classes of therapeutics to face the …

The molecular hybridization concept has recently emerged as a powerful approach in drug
discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed …

A series of Schiff bases 14–25 were designed and synthesized for evaluation of their
antibacterial properties against multi-drug resistant bacteria (MDRB). The antibacterial …

Abstract New series of pyrazolo [1, 5-a] pyrimidine derivatives 7a–i, 11a–c and Schiff bases
13a–c were synthesized and screened for their in vitro antitumor activity against three …

Schiff bases exhibited various pharmacological and biological activities such as
antibacterial, cytotoxic effects, antifungal, and antimalarial. Schiff bases were used for …

Abstract A series of chalcones 3–5, 1H-pyrazolines 6–8, N-phenylpyrazolines 9–11, and N-
acetylpyrazolines 12–14 incorporating benzofuran and pyrazole moieties were synthesized …

ABSTRACT A novel series of pyrazolo [1, 5-a] pyrimidines 14a–j and pyrazolo [1, 5-a]
quinazolines 18a, b were synthesized via condensation of 5-amino-1 H-pyrazoles 10a, b …

Exploring novel classes of antimicrobial therapeutics is an excellent approach to face the
challenge of microbial resistance. In this context, a novel series of pyrazolo [1, 5-a] …