Next-generation sequencing technology has rapidly accelerated the discovery of genetic
variants of interest in individuals with rare diseases. However, showing that these variants …

Due to the availability of genomic resources, including whole genome sequences and
numerous DNA markers in some aquaculture species, genetic improvement of important …

mRNA-based therapeutics have revolutionized the world of molecular therapy and have
proven their potential in the vaccination campaigns for SARS-CoV2 and clinical trials for …

Rare genetic diseases are a group of pathologies with often unmet clinical needs. Even if
rare by a single genetic disease (from 1/2000 to 1/more than 1,000,000), the total number of …

Model organism (MO) research provides a basic understanding of biology and disease due
to the evolutionary conservation of the molecular and cellular language of life. MOs have …

Genomewide association studies (GWAS) have improved our understanding of the genetic
architecture of common complex diseases such as osteoporosis. Nevertheless, to attribute …

A systematic knowledge of the roles of DNA repair genes at the level of the organism has
been limited due to the lack of appropriate experimental approaches using animal model …

The zebrafish is one of the most widely adopted animal models in both basic and
translational research. This popularity of the zebrafish results from several advantages such …

The zebrafish is a powerful model system for studying animal development, for modeling
genetic diseases, and for large-scale in vivo functional genetics. Because of its ease of use …

Bottlenecks in moving genomics to real-life applications also include phenomics. This is true
not only for genomics medicine and public health genomics but also in ecology and …