Introduction: Sickle cell disease is a genetically inherited disease affecting millions of people
worldwide. Patients with a severe form of the disease present with more complications and …

Objective: Males and females have been reported to show significant variation with respect
to clinical profile of sickle cell disease (SCD)(eg cardiovascular, musculoskeletal and …

Background: Hydroxyurea (HU) is the first disease-modifying drug used in the treatment of
sickle cell disease (SCD). Despite its well-documented benefits, adoption and drug …

Sickle cell disease (SCD) is a hereditary disease that comes with many complications, such
as vaso-occlusive crises and anemia. The SCD is now a public health problem due to its …

Aim: Sickle cell disease is a public health problem with a global spread. As a hereditary
disease, sickle cell disease comes with many complications, including anemia. With the …

Materials and Methods: Twenty-eight SCD patients who were diagnosed with AP during
their admission to the paediatric department at a tertiary hospital between January 2012 and …

Background: Sickle cell disease is an autosomal recessive disease characterized by an
aberrant production of hemoglobin S (HbS). The disease's presentation and severity varied …

Methods Our study involved 481 participants, including 356 SCA patients and 125 healthy
controls, who reported at the Korle-Bu Teaching Hospital, Accra, Ghana. Using a mixed …