Age-related changes in bone marrow mesenchymal stromal cells: a potential impact on osteoporosis and osteoarthritis development

P Ganguly, JJ El-Jawhari, PV Giannoudis… - Cell …, 2017 - journals.sagepub.com
Aging at the cellular level is a complex process resulting from accumulation of various
damages leading to functional impairment and a reduced quality of life at the level of the …

Markers for characterization of bone marrow multipotential stromal cells

SA Boxall, E Jones - Stem cells international, 2012 - Wiley Online Library
Given the observed efficacy of culture‐expanded multipotential stromal cells, also termed
mesenchymal stem cells (MSCs), in the treatment of graft‐versus host and cardiac disease, it …

Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration

JM Cassano, JG Kennedy, KA Ross, EJ Fraser… - Knee Surgery, Sports …, 2018 - Springer
Purpose Bone marrow concentrate (BMC) and platelet-rich plasma (PRP) are used
extensively in regenerative medicine. The aim of this study was to determine differences in …

The gap between the physiological and therapeutic roles of mesenchymal stem cells

U Galderisi, A Giordano - Medicinal research reviews, 2014 - Wiley Online Library
Several investigators have cultivated marrow stromal cells and have identified a population
of mesenchymal stem cells (MSCs). These cells expand extensively in vitro and exhibit …

Induced periosteum a complex cellular scaffold for the treatment of large bone defects

RJ Cuthbert, SM Churchman, HB Tan, D McGonagle… - Bone, 2013 - Elsevier
Objective Surgically induced periosteal membrane holds great potential for the treatment of
large bone defects representing a simple alternative to combinations of exogenous stem …

Mesenchymal stem cell subpopulations: phenotype, property and therapeutic potential

M Mo, S Wang, Y Zhou, H Li, Y Wu - Cellular and Molecular Life Sciences, 2016 - Springer
Mesenchymal stem cells (MSC) are capable of differentiating into cells of multiple cell
lineages and have potent paracrine effects. Due to their easy preparation and low …

Concise review: adult mesenchymal stromal cell therapy for inflammatory diseases: how well are we joining the dots?

MD Griffin, SJ Elliman, E Cahill, K English… - Stem …, 2013 - academic.oup.com
Mesenchymal stromal (stem) cells (MSCs) continue to be a strong area of focus for
academic-and industry-based researchers who share the goal of expanding their …

Concise review: optimizing expansion of bone marrow mesenchymal stem/stromal cells for clinical applications

AI Hoch, JK Leach - Stem cells translational medicine, 2014 - academic.oup.com
Bone marrow-derived mesenchymal stem/stromal cells (MSCs) have demonstrated success
in the clinical treatment of hematopoietic pathologies and cardiovascular disease and are …

Pre-clinical studies of bone regeneration with human bone marrow stromal cells and biphasic calcium phosphate

MÁ Brennan, A Renaud, J Amiaud… - Stem cell research & …, 2014 - Springer
Introduction Repair of large bone defects remains a significant clinical challenge. Bone
marrow stromal cells (BMSCs), a subset of which is known as bone marrow-derived …

Soliciting strategies for developing cell-based reference materials to advance mesenchymal stromal cell research and clinical translation

S Viswanathan, A Keating, R Deans… - Stem cells and …, 2014 - liebertpub.com
The mesenchymal stromal cell (MSC) field continues to rapidly progress with a number of
clinical trials initiated and completed, with some reported successes in multiple clinical …