A brief history of protein sorting prediction

H Nielsen, KD Tsirigos, S Brunak, G von Heijne - The protein journal, 2019 - Springer
Ever since the signal hypothesis was proposed in 1971, the exact nature of signal peptides
has been a focus point of research. The prediction of signal peptides and protein subcellular …

[HTML][HTML] Membrane proteins structures: A review on computational modeling tools

JG Almeida, AJ Preto, PI Koukos, AMJJ Bonvin… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Abstract Background Membrane proteins (MPs) play diverse and important functions in
living organisms. They constitute 20% to 30% of the known bacterial, archaean and …

BUSCA: an integrative web server to predict subcellular localization of proteins

C Savojardo, PL Martelli, P Fariselli… - Nucleic acids …, 2018 - academic.oup.com
Here, we present BUSCA (http://busca. biocomp. unibo. it), a novel web server that
integrates different computational tools for predicting protein subcellular localization …

Unmanned Aerial System (UAS)-based phenotyping of soybean using multi-sensor data fusion and extreme learning machine

M Maimaitijiang, A Ghulam, P Sidike, S Hartling… - ISPRS Journal of …, 2017 - Elsevier
Estimating crop biophysical and biochemical parameters with high accuracy at low-cost is
imperative for high-throughput phenotyping in precision agriculture. Although fusion of data …

DeepSig: deep learning improves signal peptide detection in proteins

C Savojardo, PL Martelli, P Fariselli, R Casadio - Bioinformatics, 2018 - academic.oup.com
Motivation The identification of signal peptides in protein sequences is an important step
toward protein localization and function characterization. Results Here, we present DeepSig …

Identification of OmpA, a Coxiella burnetii Protein Involved in Host Cell Invasion, by Multi-Phenotypic High-Content Screening

E Martinez, F Cantet, L Fava, I Norville… - PLoS …, 2014 - journals.plos.org
Coxiella burnetii is the agent of the emerging zoonosis Q fever. This pathogen invades
phagocytic and non-phagocytic cells and uses a Dot/Icm secretion system to co-opt the …

Extreme learning machines on high dimensional and large data applications: a survey

J Cao, Z Lin - Mathematical Problems in Engineering, 2015 - Wiley Online Library
Extreme learning machine (ELM) has been developed for single hidden layer feedforward
neural networks (SLFNs). In ELM algorithm, the connections between the input layer and the …

Computational modeling of membrane proteins

J Koehler Leman, MB Ulmschneider… - … Structure, Function, and …, 2015 - Wiley Online Library
The determination of membrane protein (MP) structures has always trailed that of soluble
proteins due to difficulties in their overexpression, reconstitution into membrane mimetics …

PRED-TMBB2: improved topology prediction and detection of beta-barrel outer membrane proteins

KD Tsirigos, A Elofsson, PG Bagos - Bioinformatics, 2016 - academic.oup.com
Abstract Motivation The PRED-TMBB method is based on Hidden Markov Models and is
capable of predicting the topology of beta-barrel outer membrane proteins and discriminate …

Inclusion of dyad-repeat pattern improves topology prediction of transmembrane β-barrel proteins

S Hayat, C Peters, N Shu, KD Tsirigos… - …, 2016 - academic.oup.com
Accurate topology prediction of transmembrane β-barrels is still an open question. Here, we
present BOCTOPUS2, an improved topology prediction method for transmembrane β …