Abstract Purpose of Review Cholangiocarcinoma is a rare biliary adenocarcinoma
associated with poor outcomes. Cholangiocarcinoma is subdivided into extrahepatic and …

Biliary tract cancers (BTCs) are rare with poor prognosis. Due to the advent of genomic
sequencing, new data have emerged regarding the molecular makeup of this disease. To …

Purpose: This study is an expanded and parallel clinical trial of EGFR-specific chimeric
antigen receptor–engineered autologous T (CART) cell immunotherapy (NCT01869166) to …

Biliary tract cancer accounts for< 1% of all cancers and affects chiefly an elderly population,
with predominance in men. We distinguish cholangiocarcinoma (intrahepatic, hilar and …

BACKGROUND Biliary tract cancer (BTC) is a rare and lethal disease with few therapeutic
options. Preclinical data suggest that the epidermal growth factor receptor (EGFR) pathway …

Addition of cetuximab showed trend, but not significantly, to improve the therapeutic effects
of gemcitabine and oxaliplatin combination for advanced biliary tract cancer in current …

Cholangiocarcinoma (CCA) is a relatively rare malignancy that arises from the epithelial
cells of the intrahepatic, perihilar and distal biliary tree. Intrahepatic CCA (ICC) represents …

In the oncology landscape, cholangiocarcinoma is a challenging disease in terms of both
diagnosis and treatment. Besides anamnesis and clinical examination, a definitive diagnosis …

Biliary tract cancer, carcinoma of the extrahepatic bile ducts, carcinoma of the gall bladder,
ampullary carcinoma and intrahepatic cholangiocarcinoma are often identified at an …

Gallbladder carcinoma (GBC) is the most aggressive gastrointestinal malignancy throughout
the world, with wide geographical variance. It is the subtype of biliary tract malignancy that …