Environment changes, aflatoxins, and health issues, a review

R Valencia-Quintana, M Milić, D Jakšić… - International Journal of …, 2020 - mdpi.com
Crops contaminated by aflatoxins (AFs), the toxic and carcinogenic mycotoxins produced
namely by Aspergillus flavus and Aspergillus parasiticus, have severe impacts on human …

Regulation of cytochrome P450 expression by microRNAs and long noncoding RNAs: Epigenetic mechanisms in environmental toxicology and carcinogenesis

D Li, WH Tolleson, D Yu, S Chen, L Guo… - … Science and Health …, 2019 - Taylor & Francis
Environmental exposures to hazardous chemicals are associated with a variety of human
diseases and disorders, including cancers. Phase I metabolic activation and detoxification …

Epigenetic alterations caused by aflatoxin b1: a public health risk in the induction of hepatocellular carcinoma

RG Ferreira, MV Cardoso, KM De Souza Furtado… - Translational …, 2019 - Elsevier
Aflatoxin B1 (AFB1) is currently the most commonly studied mycotoxin due to its great
toxicity, its distribution in a wide variety of foods such as grains and cereals and its …

miR-515–5p suppresses HCC migration and invasion via targeting IL6/JAK/STAT3 pathway

J Ni, H Zheng, Y Ou, Y Tao, Z Wang, L Song, H Yan… - Surgical Oncology, 2020 - Elsevier
MicroRNAs (miRNAs) have been identified as critical modulators of cell migration and
invasion, which are the major causes of cancer progression including hepatocellular …

[HTML][HTML] Aflatoxin B1-induced hepatotoxicity through mitochondrial dysfunction, oxidative stress, and inflammation as central pathological mechanisms: a review of …

TP Moloi, K Ziqubu, SE Mazibuko-Mbeje, NH Mabaso… - Toxicology, 2024 - Elsevier
Abstract Aflatoxin B 1 (AFB 1) is a class of mycotoxin known to contaminate agricultural
products, animal feed and animal food products, subsequently causing detrimental effects …

Involvement of ahr pathway in toxicity of aflatoxins and other mycotoxins

F Arenas-Huertero, M Zaragoza-Ojeda… - Frontiers in …, 2019 - frontiersin.org
The purpose of this review is to present information about the role of activation of aflatoxins
and other mycotoxins, of the aryl hydrocarbon receptor (AhR) pathway. Aflatoxins and other …

miR-34a screened by miRNA profiling negatively regulates Wnt/β-catenin signaling pathway in Aflatoxin B1 induced hepatotoxicity

L Zhu, J Gao, K Huang, Y Luo, B Zhang, W Xu - Scientific reports, 2015 - nature.com
Abstract Aflatoxin-B1 (AFB1), a hepatocarcinogenic mycotoxin, was demonstrated to induce
the high rate of hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) participate in the …

Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use

C Michailidi, M Hayashi, S Datta, T Sen, K Zenner… - Cancer prevention …, 2015 - AACR
Exposure to toxicants leads to cumulative molecular changes that overtime increase a
subject's risk of developing urothelial carcinoma. To assess the impact of arsenic exposure …

Serum miRNAs as predictive and preventive biomarker for pre-clinical hepatocellular carcinoma

L Li, J Chen, X Chen, J Tang, H Guo, X Wang, J Qian… - Cancer Letters, 2016 - Elsevier
The extremely poor prognosis of patients with symptomatic hepatocellular carcinoma (HCC)
diagnosed clinically at advanced stages suggests an urgent need for biomarkers that can be …

Role of microRNAs in lung carcinogenesis induced by asbestos

R Bersimbaev, O Bulgakova, A Aripova… - Journal of personalized …, 2021 - mdpi.com
MicroRNAs are a class of small noncoding endogenous RNAs 19–25 nucleotides long,
which play an important role in the post-transcriptional regulation of gene expression by …