The pineal product melatonin has remarkable antioxidant properties. It is secreted during
darkness and plays a key role in various physiological responses including regulation of …

Circadian rhythms control the life of virtually all organisms. They regulate numerous aspects
ranging from cellular processes to reproduction and behavior. Besides the light-dark cycle …

Myopia has become a major public health concern, particularly across much of Asia. It has
been shown in multiple studies that outdoor activity has a protective effect on myopia …

Background Clinical psychiatry has always been limited by the lack of objective tests to
substantiate diagnoses and a lack of specific treatments that target underlying …

Background In bright light, mammals use a distinct photopigment (melanopsin) to measure
irradiance for centrally mediated responses such as circadian entrainment. We aimed to …

Light is the visible part of the electromagnetic radiation within a range of 380–780 nm;(400–
700 on primates retina). In vertebrates, the retina is adapted to capturing light photons and …

The purpose of this work is to investigate the efficacy of exogenous melatonin in the
treatment of sleep disorders in patients with neurodegenerative disease. We searched …

It is now a decade since the first published reports that a small proportion of mammalian
retinal ganglion cells are directly photoresponsive. These cells have been termed …

Delirium is a serious neuropsychiatric syndrome of acute onset that occurs in approximately
one in five general hospital patients and is associated with serious adverse outcomes that …

The mammalian retina is the most unique tissue among those that display robust
circadian/diurnal oscillations. The retina is not only a light sensing tissue that relays light …