Mesenchymal stem cell-based therapy for rheumatoid arthritis

M Sarsenova, A Issabekova, S Abisheva… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of
cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to …

Biological characteristics of umbilical cord mesenchymal stem cells and its therapeutic potential for hematological disorders

Y Shang, H Guan, F Zhou - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Umbilical cord mesenchymal stem cells (UC-MSCs) are a class of multifunctional stem cells
isolated and cultured from umbilical cord. They possessed the characteristics of highly self …

Stem cell–based therapies for sepsis

C Keane, M Jerkic, JG Laffey - Anesthesiology, 2017 - pubs.asahq.org
Sepsis is a life-threatening syndrome resulting in shock and organ dysfunction stemming
from a microbial infection. Sepsis has a mortality of 40% and is implicated in half of all in …

Adipose stromal cells bioproducts as cell-free therapies: manufacturing and therapeutic dose determine in vitro functionality

R Skovronova, E Scaccia, S Calcat-i-Cervera… - Journal of Translational …, 2023 - Springer
Background Extracellular vesicles (EV) are considered a cell-free alternative to
mesenchymal stromal cell (MSC) therapy. Numerous reports describe the efficacy of EV in …

Infrapatellar fat pad-derived mesenchymal stromal cell product for treatment of knee osteoarthritis: a first-in-human study with evaluation of the potency marker

HH Chen, YC Chen, SN Yu, WL Lai, YS Shen… - Cytotherapy, 2022 - Elsevier
Background aims Infrapatellar fat pad-derived mesenchymal stromal cells (IFP-MSCs) have
not yet been used in a human clinical trial. In this open-label phase 1 study, patients with …

Mesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor d-1 …

X Zhang, Y Yang, L Zhang, Y Lu, Q Zhang… - Journal of hematology & …, 2017 - Springer
Background Although blinatumomab, a bispecific T cell engaging antibody, exhibits high
clinical response rates in patients with relapsed or refractory B-precursor acute …

The effect of TLR3 priming conditions on MSC immunosuppressive properties

T Tolstova, E Dotsenko, P Kozhin, S Novikova… - Stem Cell Research & …, 2023 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) have regenerative and
immunomodulatory properties, making them suitable for cell therapy. Toll-like receptors …

[HTML][HTML] Clinical applications of mesenchymal stromal cell-based therapies for pulmonary diseases: An Update and Concise Review

X Chen, F Wang, Z Huang, Y Wu, J Geng… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Lung disorders are a leading cause of morbidity and death worldwide. For many disease
conditions, no effective and curative treatment options are available. Mesenchymal stromal …

Interactions of mesenchymal stromal/stem cells and immune cells following MSC-based therapeutic approaches in rheumatoid arthritis

S Dehnavi, M Sadeghi, JT Afshari, M Mohammadi - Cellular Immunology, 2023 - Elsevier
Rheumatoid arthritis (RA) is considered to be a degenerative and progressive autoimmune
disorder. Although several medicinal regimens are used to treat RA, potential adverse …

Cellular therapies for the treatment and prevention of SARS-CoV-2 infection

SR Conway, MD Keller… - Blood, The Journal of the …, 2022 - ashpublications.org
Patients with blood disorders who are immune suppressed are at increased risk for infection
with severe acute respiratory syndrome coronavirus 2. Sequelae of infection can include …