K Chen, N Rajewsky - Nature Reviews Genetics, 2007 - nature.com
Abstract Changes in the patterns of gene expression are widely believed to underlie many of the phenotypic differences within and between species. Although much emphasis has been …
Introduction: MicroRNAs (miRNAs), which are evolutionarily conserved, and endogenous non-coding RNAs, participate in the post-transcriptional regulation of eukaryotic genes. The …
Since the first description of RNA interference (RNAi) in animals less than a decade ago, there has been rapid progress towards its use as a therapeutic modality against human …
DJ Obbard, KHJ Gordon, AH Buck… - … Transactions of the …, 2009 - royalsocietypublishing.org
RNA interference (RNAi) is an important defence against viruses and transposable elements (TEs). RNAi not only protects against viruses by degrading viral RNA, but hosts and viruses …
MA Lindsay - Trends in immunology, 2008 - cell.com
microRNA (miRNA)-mediated RNA interference has been identified as a novel mechanism that regulates protein expression at the translational level. Recent publications have …
T Zhang, Z Yang, P Kusumanchi, S Han… - Frontiers in …, 2020 - frontiersin.org
MicroRNAs are small non-coding RNAs that range in length from 18 to 24 nucleotides. As one of the most extensively studied microRNAs, microRNA-21 (miR-21) is highly expressed …
HF Lodish, B Zhou, G Liu, CZ Chen - Nature Reviews Immunology, 2008 - nature.com
MicroRNAs (miRNAs) are an abundant class of evolutionarily conserved small non-coding RNAs that are thought to control gene expression by targeting mRNAs for degradation or …
M Wakiyama, K Takimoto, O Ohara… - Genes & …, 2007 - genesdev.cshlp.org
MicroRNAs (miRNAs) are incorporated into miRNP complexes and regulate protein expression post-transcriptionally through binding to 3′-untranslated regions of target …
Sleep deprivation disrupts the lives of millions of people every day and has a profound impact on the molecular biology of the brain. These effects begin as changes within a …