Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity

KH Collins, W Herzog, GZ MacDonald… - Frontiers in …, 2018 - frontiersin.org
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …

[HTML][HTML] Kupffer cells in the liver

LJ Dixon, M Barnes, H Tang, MT Pritchard… - Comprehensive …, 2013 - ncbi.nlm.nih.gov
Kupffer cells are a critical component of the mononuclear phagocytic system and are central
to both the hepatic and systemic response to pathogens. Kupffer cells are reemerging as …

Evolving therapies for liver fibrosis

D Schuppan, YO Kim - The Journal of clinical investigation, 2013 - Am Soc Clin Investig
Fibrosis is an intrinsic response to chronic injury, maintaining organ integrity when extensive
necrosis or apoptosis occurs. With protracted damage, fibrosis can progress toward …

Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta …

G Musso, M Cassader, F Rosina, R Gambino - Diabetologia, 2012 - Springer
Aims/hypothesis Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum
ranging from simple steatosis to non-alcoholic steatohepatitis (NASH): NAFLD causes an …

Brain metabolic dysfunction at the core of Alzheimer's disease

SM de la Monte, M Tong - Biochemical pharmacology, 2014 - Elsevier
Growing evidence supports the concept that Alzheimer's disease (AD) is fundamentally a
metabolic disease with molecular and biochemical features that correspond with diabetes …

Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2

K Miura, L Yang, N van Rooijen… - American Journal of …, 2012 - journals.physiology.org
Inflammatory cell infiltration in the liver is a hallmark of nonalcoholic steatohepatitis (NASH).
The chemokine-chemokine receptor interaction induces inflammatory cell recruitment. CC …

Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial

S Chen, X Zhao, J Wan, L Ran, Y Qin, X Wang… - Pharmacological …, 2015 - Elsevier
Ampelopsis grossedentata, a medicinal and edible plant, has been widely used in China for
hundreds of years, and dihydromyricetin is the main active ingredient responsible for its …

Metabolic syndrome and risk factors for non-alcoholic fatty liver disease

MRA Souza, MFFM Diniz… - Arquivos de …, 2012 - SciELO Brasil
CONTEXT: Non-alcoholic fatty liver disease (NAFLD), hepatic manifestation of metabolic
syndrome, has been considered the most common liver disease nowadays, which is also …

Liver and diabetes. A vicious circle

P Loria, A Lonardo, F Anania - Hepatology research, 2013 - Wiley Online Library
The complex and bi‐directional relationship linking the liver and diabetes has recently
gained intense new interest. This critical review of the published work aims to highlight the …

Bisphenol A alters gut microbiome: comparative metagenomics analysis

KP Lai, YT Chung, R Li, HT Wan, CKC Wong - Environmental Pollution, 2016 - Elsevier
Mounting evidence has shown that an alteration of the gut microbiota is associated with diet,
and plays an important role in animal health and metabolic diseases. However, little is …