Use of standardized units for a correct interpretation of IC50 values obtained from the inhibition of the DPPH radical by natural antioxidants

F Martinez-Morales, AJ Alonso-Castro… - Chemical Papers, 2020 - Springer
Abstract The 2, 2′-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay is a valid
and commonly test used to measure the total antioxidant capacity in natural extracts. The …

[HTML][HTML] Study of the effect of extract of Thymus vulgaris on anxiety in male rats

A Komaki, F Hoseini, S Shahidi, N Baharlouei - Journal of traditional and …, 2016 - Elsevier
There is some evidence in traditional medicine for the effectiveness of Thymus vulgaris
(百里香 bǎi lǐ xiāng) in the treatment of anxiety in humans. The elevated plus-maze (EPM) …

Protective effect of gallic acid against arsenic-induced anxiety−/depression-like behaviors and memory impairment in male rats

N Samad, S Jabeen, I Imran, I Zulfiqar, K Bilal - Metabolic Brain Disease, 2019 - Springer
The purpose of the present study is to determine the effects of gallic acid (GA) on sodium
arsenite (iAS)-induced behavior deficits and memory alteration in male rats. Thirty six …

Chemical composition, antioxidant and antibacterial activity of Crataegus monogyna leaves' extracts

F Belabdelli, N Bekhti, A Piras… - Natural Product …, 2022 - Taylor & Francis
Crataegus monogyna is an important plant of the Rosaceae family, widely used in traditional
medicine to treat various conditions such as cardiovascular diseases, cancer, diabetes …

The anxiolytic-like effect of rutin in rats involves GABAA receptors in the basolateral amygdala

A Hernandez-Leon, ME González-Trujano… - Behavioural …, 2017 - journals.lww.com
Rutin is a bioflavonoid found in medicinal plants used to reduce anxiety. Evidence is lacking
of rutin's anxiolytic-like activity, putative mechanism (s) of action, and neural sites of effects …

Identification of potential targets of cinnamon for treatment against Alzheimer's disease-related GABAergic synaptic dysfunction using network pharmacology

D Qian, Q Wang, S Lin, Y Li, X Gu, C Xia, Y Xu… - Scientific Reports, 2022 - nature.com
Cinnamon aqueous extract's active substance base remains unclear and its mechanisms,
mainly the therapeutic target of anti-Alzheimer's disease (AD)-related GABAergic synaptic …

The Effectiveness of Crataegus orientalis M Bieber. (Hawthorn) Extract Administration in Preventing Alveolar Bone Loss in Rats with Experimental Periodontitis

M Hatipoğlu, M Sağlam, S Köseoğlu, E Köksal… - PLoS …, 2015 - journals.plos.org
The purpose of this animal study was to evaluate the effects of hawthorn (Crataeus orientalis
M Bieber.) extract on serum oxidative status and alveolar bone loss in experimental …

Untargeted metabolomic profiling of three Crataegus species (hawthorn) and their in vitro biological activities

G Rocchetti, B Senizza, G Zengin… - Journal of the …, 2020 - Wiley Online Library
BACKGROUND In this investigation, the chemical and biological profiles of three Turkish
Crataegus species (Crataegus orientalis, Crataegus szovitsii and Crataegus tanacetifolia) …

Cyanidin prevents MDPV withdrawal-induced anxiety-like effects and dysregulation of cytokine systems in rats

S Inan, JJ Meissler, A Shekarabi, J Foss, S Wiah… - Brain research, 2023 - Elsevier
Psychostimulant exposure and withdrawal cause neuroimmune dysregulation and anxiety
that contributes to dependence and relapse. Here, we tested the hypothesis that withdrawal …

[HTML][HTML] Evaluation of antioxidant, toxicological and anxiolytic-like effect of ethanolic extracts of Ziziphus cotinifolia Reissek in adult zebrafish (Danio rerio)

DV de Azevedo, DM Silva, FEA Magalhães… - Phytomedicine Plus, 2024 - Elsevier
Abstract Background The GABAergic and serotoninergic neurotransmission pathways are
involved in the control of anxiety and ensure emotional balance. Some plant species have …