Prior to 2001 there was no standard for early management of severe sepsis and septic
shock in the emergency department. In the presence of standard or usual care, the …

Studies of acute myocardial infarction, trauma, and stroke have been translated into
improved outcomes by earlier diagnosis and application of therapy at the most proximal …

METHODS The recommendations were developed as a synthesis and update of evidence
from the literature. They are based on the FIGO Safe Motherhood and Newborn Health …

Objective: Serial lactate concentrations can be used to examine disease severity in the
intensive care unit. This study examines the clinical utility of the lactate clearance before …

Introduction Isolated vital signs (for example, heart rate or systolic blood pressure) have
been shown unreliable in the assessment of hypovolemic shock. In contrast, the Shock …

Methods: We performed a retrospective analysis of a cohort of adult ED patients at an
academic community trauma center with 95,000 annual visits, from February 1st, 2007 to …

Background: In the prehospital environment, the failure of medical providers to recognize
latent physiologic derangement in patients with compensated shock may risk undertriage …

Introduction The recognition and management of hypovolemic shock still remain an
important task during initial trauma assessment. Recently, we have questioned the validity of …

Objectives To compare the predictive value of the shock index (SI) with conventional vital
signs in postpartum haemorrhage (PPH), and to establish 'alert'thresholds for use in low …

BACKGROUND Systolic blood pressure (SBP), heart rate (HR), and respiratory rate are poor
predictors of trauma outcome. We postulate that HR/SBP (shock index [SI]) and novel new …