Diabetic vascular complications can affect both microvascular and macrovascular. Diabetic
microvascular complications, such as diabetic nephropathy, diabetic retinopathy, diabetic …

The diverse members of the CCN family now designated as CCN1 (CYR61), CCN2 (CTGF),
CCN3 (NOV), CCN4 (WISP1), CCN5 (WISP2), CCN6 (WISP3) are a conserved matricellular …

Compromised vascular endothelial barrier function is a salient feature of diabetic
complications such as sight-threatening diabetic macular edema (DME). Current standards …

The rapid advancements in gene therapy have opened up new possibilities for treating
genetic disorders, including Duchenne muscular dystrophy, thalassemia, cystic fibrosis …

Diabetic retinopathy (DR) is the most common retinal vascular disease. Proliferative DR
(PDR) is the aggressive stage of DR with angiogenesis as a pathological hallmark, which is …

To investigate the molecular mechanism of communication network factor 1 (CCN1)
regulating pentylenetetrazol (PTZ)-induced epileptogenesis, deepen the understanding of …

The purpose of this study is to investigate whether secreted frizzled-related protein 5
(SFRP5) affects the proliferation, migration and angiogenesis of human umbilical vein …

Diabetic retinopathy (DR) is a leading cause of blindness, and ferroptosis may be an
essential component of the pathological process of DR. In this study, we aimed to screen five …

Purpose: Proliferative diabetic retinopathy (PDR) is characterized by retinal new vessel
formation, pointing to the importance of the antiangiogenic treatment in PDR. Hepatocyte …

The extracellular matrix is an essential component and constitutes a dynamic
microenvironment of the vessel wall with an indispensable role in vascular homeostasis and …