Importance Obsessive-compulsive disorder (OCD) is a common and often debilitating
psychiatric illness. Recent advances in the understanding of the neuroscience of OCD have …

Mutations in the genes encoding Leucine Rich Repeat (LRR) containing proteins are
associated with over sixty human diseases; these include high myopia, mitochondrial …

Obsessive–compulsive disorder (OCD) affects 1–2% of the population, and, as with other
complex neuropsychiatric disorders, it is thought that rare variation contributes to its genetic …

Abstract Children conceived using Assisted Reproductive Technologies (ART) have a
higher incidence of growth and birth defects, attributable in part to epigenetic perturbations …

Trans-synaptic cell-adhesion molecules are critical for governing various stages of synapse
development and specifying neural circuit properties via the formation of multifarious …

SLITRK2 is a single-pass transmembrane protein expressed at postsynaptic neurons that
regulates neurite outgrowth and excitatory synapse maintenance. In the present study, we …

Behavioural inflexibility is a symptom of neuropsychiatric and neurodegenerative disorders
such as Obsessive-Compulsive Disorder, Autism Spectrum Disorder and Alzheimer's …

The brain harbors billions of neurons that form distinct neural circuits with exquisite
specificity. Specific patterns of connectivity between distinct neuronal cell types permit the …

Tourette syndrome (TS) and obsessive-compulsive disorder (OCD) are two neuropsychiatric
disorders that frequently co-occur. Previous evidence suggests a shared genetic diathesis …

Gilles de la Tourette syndrome (GTS) is a childhood-onset neurodevelopmental and-
psychiatric tic-disorder of complex etiology which is often comorbid with obsessive …