Schistosoma mansoni vaccine candidates identified by unbiased phage display screening in self-cured rhesus macaques

D Woellner-Santos, AC Tahira, JVM Malvezzi, V Mesel… - npj Vaccines, 2024 - nature.com
Schistosomiasis, a challenging neglected tropical disease, affects millions of people
worldwide. Developing a prophylactic vaccine against Schistosoma mansoni has been …

Long non-coding RNAs are essential for Schistosoma mansoni pairing-dependent adult worm homeostasis and fertility

GO Silveira, HS Coelho, ASA Pereira… - Plos …, 2023 - journals.plos.org
The trematode parasite Schistosoma mansoni causes schistosomiasis, which affects over
200 million people worldwide. Schistosomes are dioecious, with egg laying depending on …

Dynamic profiles of lncRNAs reveal a functional natural antisense RNA that regulates the development of Schistosoma japonicum

S Cheng, Y You, X Wang, C Yi, W Zhang, Y Xie… - Plos …, 2024 - journals.plos.org
Schistosomes are flatworm parasites that undergo a complex life cycle involving two hosts.
The regulation of the parasite's developmental processes relies on both coding RNAs and …

Long Non-Coding RNA Levels Are Modulated in Schistosoma mansoni following In Vivo Praziquantel Exposure

P Jardim Poli, A Fischer-Carvalho, AC Tahira… - Non-coding RNA, 2024 - mdpi.com
Schistosomiasis is a disease caused by trematodes of the genus Schistosoma that affects
over 200 million people worldwide. For decades, praziquantel (PZQ) has been the only …

Chromatin structure around long non-coding RNA (lncRNA) genes in Schistosoma mansoni gonads

R de Carvalho Augusto, T Quack, CG Grevelding… - bioRxiv, 2024 - biorxiv.org
In this study, we employed a total of eight distinct modifications of histone proteins
(H3K23ac, H3K27me3, H3K36me3, H3K4me3, H3K9ac, H3K9me3, H4K12ac, and …

[PDF][PDF] Daisy Woellner Santos

DW Santos - teses.usp.br
Abstract Woellner-Santos, D. Identification of antigenic epitopes of the parasite Schistosoma
mansoni targeted by the immune response of self-cured and reinfected-resistant rhesus …