Molecular mechanism of VEGF and its role in pathological angiogenesis

A Ahmad, MI Nawaz - Journal of Cellular Biochemistry, 2022 - Wiley Online Library
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …

Ultra-widefield retinal imaging: an update on recent advances

SN Patel, A Shi, TD Wibbelsman… - Therapeutic advances …, 2020 - journals.sagepub.com
The development of ultra-widefield retinal imaging has accelerated our understanding of
common retinal diseases. As we continue to validate the diagnostic and prognostic …

Effect of intravitreous anti–vascular endothelial growth factor vs sham treatment for prevention of vision-threatening complications of diabetic retinopathy: the protocol …

RK Maturi, AR Glassman, K Josic… - JAMA …, 2021 - jamanetwork.com
Importance The role of anti–vascular endothelial growth factor injections for the
management of nonproliferative diabetic retinopathy (NPDR) without center-involved …

Association of predominantly peripheral lesions on ultra-widefield imaging and the risk of diabetic retinopathy worsening over time

DM Marcus, PS Silva, D Liu, LP Aiello… - JAMA …, 2022 - jamanetwork.com
Importance Ultra-widefield (UWF) imaging improves the ability to identify peripheral diabetic
retinopathy (DR) lesions compared with standard imaging. Whether detection of …

Association of ultra-widefield fluorescein angiography–identified retinal nonperfusion and the risk of diabetic retinopathy worsening over time

PS Silva, DM Marcus, D Liu, LP Aiello… - JAMA …, 2022 - jamanetwork.com
Importance Presence of predominantly peripheral diabetic retinopathy (DR) lesions on ultra-
widefield fluorescein angiography (UWF-FA) was associated with greater risk of DR …

[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Olives dataset: Ophthalmic labels for investigating visual eye semantics

M Prabhushankar, K Kokilepersaud… - Advances in …, 2022 - proceedings.neurips.cc
Clinical diagnosis of the eye is performed over multifarious data modalities including scalar
clinical labels, vectorized biomarkers, two-dimensional fundus images, and three …

Update on the management of diabetic retinopathy: Anti-VEGF agents for the prevention of complications and progression of nonproliferative and proliferative …

TA Bahr, SJ Bakri - Life, 2023 - mdpi.com
Diabetic retinopathy (DR) is a microvascular disease caused by poorly controlled blood
glucose, and it is a leading cause of vision loss in people with diabetes. In this review we …

Assessment of fluorescein angiography nonperfusion in eyes with diabetic retinopathy using ultrawide field retinal imaging

PS Silva, D Liu, AR Glassman, LP Aiello, S Grover… - Retina, 2022 - journals.lww.com
Purpose: Evaluate association of retinal nonperfusion (NP) on ultrawide field (UWF)
fluorescein angiography (FA) with diabetic retinopathy (DR) severity and predominantly …

Intravitreal anti-vascular endothelial growth factor agents for the treatment of diabetic retinopathy: a review of the literature

I Chatziralli, A Loewenstein - Pharmaceutics, 2021 - mdpi.com
Background: Diabetic retinopathy (DR) is the leading cause of blindness in the working-age
population. The purpose of this review is to gather the existing literature regarding the use of …