Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Nanotechnology approaches for global infectious diseases

AR Kirtane, M Verma, P Karandikar, J Furin… - Nature …, 2021 - nature.com
Infectious diseases are a major driver of morbidity and mortality globally. Treatment of
malaria, tuberculosis and human immunodeficiency virus infection are particularly …

Surface design for antibacterial materials: from fundamentals to advanced strategies

W Li, ES Thian, M Wang, Z Wang, L Ren - Advanced Science, 2021 - Wiley Online Library
Healthcare‐acquired infections as well as increasing antimicrobial resistance have become
an urgent global challenge, thus smart alternative solutions are needed to tackle bacterial …

Targeting strategies for tissue-specific drug delivery

Z Zhao, A Ukidve, J Kim, S Mitragotri - Cell, 2020 - cell.com
Off-target effects of systemically administered drugs have been a major hurdle in designing
therapies with desired efficacy and acceptable toxicity. Developing targeting strategies to …

Nanoparticles as therapeutic options for treating multidrug-resistant bacteria: research progress, challenges, and prospects

IE Mba, EI Nweze - World Journal of Microbiology and Biotechnology, 2021 - Springer
Resistance to antimicrobial agents has been alarming in recent years and poses a huge
public health threat globally according to the WHO. The increase in morbidity and mortality …

Infection microenvironment-related antibacterial nanotherapeutic strategies

Z Wang, X Liu, Y Duan, Y Huang - Biomaterials, 2022 - Elsevier
The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

Treatment of MRSA-infected osteomyelitis using bacterial capturing, magnetically targeted composites with microwave-assisted bacterial killing

Y Qiao, X Liu, B Li, Y Han, Y Zheng, KWK Yeung… - Nature …, 2020 - nature.com
Owing to the poor penetration depth of light, phototherapy, including photothermal and
photodynamic therapies, remains severely ineffective in treating deep tissue infections such …

Nano-based drug delivery or targeting to eradicate bacteria for infection mitigation: a review of recent advances

YC Yeh, TH Huang, SC Yang, CC Chen… - Frontiers in …, 2020 - frontiersin.org
Pathogenic bacteria infection is a major public health problem due to the high morbidity and
mortality rates, as well as the increased expenditure on patient management. Although there …

Recent innovations in bacterial infection detection and treatment

C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …

Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy

DW Zheng, X Dong, P Pan, KW Chen, JX Fan… - Nature biomedical …, 2019 - nature.com
The microbiota in the human gut is strongly correlated with the progression of colorectal
cancer (CRC) and with therapeutic responses to CRC. Here, by leveraging the higher …