Discovery of Nanosota-9 as anti-Omicron nanobody therapeutic candidate
Omicron subvariants of SARS-CoV-2 continue to pose a significant global health threat.
Nanobodies, single-domain antibodies derived from camelids, are promising therapeutic …
Nanobodies, single-domain antibodies derived from camelids, are promising therapeutic …
Learned features of antibody-antigen binding affinity
Defining predictors of antigen-binding affinity of antibodies is valuable for engineering
therapeutic antibodies with high binding affinity to their targets. However, this task is …
therapeutic antibodies with high binding affinity to their targets. However, this task is …
Viral capsid, antibody, and receptor interactions: experimental analysis of the antibody escape evolution of canine parvovirus
RA López-Astacio, OF Adu, DJ Goetschius… - Journal of …, 2023 - Am Soc Microbiol
Canine parvovirus (CPV) is a small nonenveloped single-stranded DNA virus that causes
serious diseases in dogs worldwide. The original strain of the virus (CPV-2) emerged in …
serious diseases in dogs worldwide. The original strain of the virus (CPV-2) emerged in …
A Candidate DNA Vaccine Encoding the Native SARS-CoV-2 Spike Protein Induces Anti-Subdomain 1 Antibodies
A Frische, V Gunalan, KA Krogfelt, A Fomsgaard… - Vaccines, 2023 - mdpi.com
The ideal vaccine against viral infections should elicit antibody responses that protect
against divergent strains. Designing broadly protective vaccines against SARS-CoV-2 and …
against divergent strains. Designing broadly protective vaccines against SARS-CoV-2 and …
Quantification of full and empty particles of adeno-associated virus vectors via a novel dual fluorescence-linked immunosorbent assay
S Soth, M Takakura, M Suekawa, T Onishi… - … Therapy Methods & …, 2024 - cell.com
The adeno-associated virus (AAV) vector is one of the most advanced platforms for gene
therapy because of its low immunogenicity and non-pathogenicity. The concentrations of …
therapy because of its low immunogenicity and non-pathogenicity. The concentrations of …
Obtaining a high titer of polyclonal antibodies from rats to the SARS-CoV-2 nucleocapsid protein and its N-and C-terminal domains for diagnostic test development
MT de Almeida, AP Barbosa, CG Bomfim… - Journal of …, 2023 - Elsevier
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is an
enveloped, plus-stranded RNA virus responsible for the Coronavirus Disease 2019 (COVID …
enveloped, plus-stranded RNA virus responsible for the Coronavirus Disease 2019 (COVID …
Deciphering the rule of antigen-antibody amino acid interaction
M Jiang, C Fang, Y Ma - Frontiers in Immunology, 2023 - frontiersin.org
Purpose Antigenic drift is the biggest challenge for mutagenic RNA virus vaccine
development. The primary purpose is to determine the IEMM (immune escape mutation …
development. The primary purpose is to determine the IEMM (immune escape mutation …
[HTML][HTML] Investigation of Reasons for the Reluctance to get Vaccinated with COVID-19 in the General Population in the South of Kerman Province (A Cross-sectional …
Aim This study aimed to determine the reasons for reluctance to get vaccinated against
COVID-19 in the general population in the south of Kerman Province. Background …
COVID-19 in the general population in the south of Kerman Province. Background …
Overcoming Variants Resistance in Monoclonal Antibody for Antiviral Therapy
Monoclonal antibody (mAb) therapy has revolutionized the treatment of various diseases,
including cancer and autoimmune disorders. However, the emergence of SARS-CoV-2 …
including cancer and autoimmune disorders. However, the emergence of SARS-CoV-2 …