Associating CYP2A6 structural variants with ovarian and lung cancer risk in the UK Biobank: replication and extension

AWR Langlois, JG Pouget, J Knight… - European Journal of …, 2024 - nature.com
CYP2A6 is a polymorphic enzyme that inactivates nicotine; structural variants (SVs) include
gene deletions and hybrids with the neighboring pseudogene CYP2A7. Two studies found …

Comparison of the diagnostic significance of cerebrospinal fluid metagenomic next-generation sequencing copy number variation analysis and cytology in …

L Zhang, K Fang, H Ren, S Fan, J Wang, H Guan - BMC neurology, 2024 - Springer
Background Diagnosis and monitoring of leptomeningeal malignancy remain challenging,
and are usually based on neurological, radiological, cerebrospinal fluid (CSF) and …

DNA Double-Strand Break Repair Inhibitors: YU238259, A12B4C3 and DDRI-18 Overcome the Cisplatin Resistance in Human Ovarian Cancer Cells, but Not under …

A Macieja, I Gulbas, T Popławski - Current Issues in Molecular Biology, 2023 - mdpi.com
Cisplatin (CDDP) is the cornerstone of standard treatment for ovarian cancer. However, the
resistance of ovarian cancer cells to CDDP leads to an inevitable recurrence. One of the …

FASTKD1 as a diagnostic and prognostic biomarker for STAD: Insights into m6A modification and immune infiltration

Y Yang, Y Gao, XS Liu, ZM Huang… - Experimental and …, 2024 - spandidos-publications.com
Fas‑activated serine/threonine kinase domain 1 (FASTKD1), a known modulator of
mitochondrial‑mediated cell death and survival processes, has garnered attention for its …

[HTML][HTML] Update Breast Cancer 2023 Part 1–Early Stage Breast Cancer

AD Hartkopf, TN Fehm, M Welslau… - Geburtshilfe und …, 2023 - thieme-connect.com
Mit den Zulassungen von Abemaciclib (monarchE-Studie) und Olaparib (OlympiA-Studie) in
der adjuvanten Therapiesituation haben sich die Therapiestandards bei der Behandlung …

Comparison of the Diagnostic Significance of CSF Metagenomic Next-generation Sequencing Copy Number Variation Analysis and Cytology in Leptomeningeal …

L Zhang, K Fang, H Ren, S Fan, J Wang, H Guan - 2023 - researchsquare.com
Purpose The early diagnosis of leptomeningeal malignancy remains a formidable challenge
in clinical practice. This study aimed to investigate the diagnostic potential of CSF …

FASTKD1 is a diagnostic and prognostic biomarker for STAD associated with m6A modification and immune infiltration

Y Yang, Y Gao, XS Liu, Y Zhang, YH Zhang, ZY Liu… - 2023 - researchsquare.com
Background Fas Activated Serine/Threonine Kinase Domains 1 (FASTKD1), a known
modulator of mitochondrial-mediated cell death and survival processes, has garnered …