Background The mechanisms by which the inhalational general anesthetics isoflurane and
xenon exert their effects are unknown. Moreover, there have been surprisingly few …

Increasing levels of anesthesia are thought to produce a progressive loss of brain
responsiveness to external stimuli. Here, we present the first report of a state window within …

1. The effects of the volatile anaesthetics enflurane, halothane and isoflurane on gamma‐
aminobutyric acid (GABA) A receptor‐mediated chloride currents were studied in cultured rat …

Status epilepticus is a common neurological emergency, with overall mortality around 20%.
Over half of cases are first time presentations of seizures. The pathological process by which …

Background Recent evidence for a presynaptic depression of glutamate release produced
by volatile anesthetics prompted the current study of isoflurane and halothane effects on …

Simple Summary The humaneness, and therefore suitability, of any particular agent or
method used to produce unconsciousness in animals, whether for anesthesia, euthanasia …

Background Isoflurane inhibits the excitatory postsynaptic current (EPSC) at many synapses.
Accumulated evidence suggests the involvement of a presynaptic mechanism. However, the …

Background: Effects of volatile anesthetic agents on N-meth-yl-D-aspartate (NMDA) receptor–
mediated excitatory synaptic transmission have not been well characterized. The authors …

Molecular and cellular evidence argues that a heterodimer between two ABC transporters,
the White protein and the Brown protein, is responsible for pumping guanine into pigment …

Optogenetic techniques provide an unprecedented ability to precisely manipulate neural
activity in the context of complex neural circuitry. Although the toolbox of optogenetic probes …