Renal fibrosis is a common feature of chronic kidney disease (CKD), and can lead to the
destruction of normal renal structure and loss of kidney function. Little progress has been …

Aldehydes are widespread in the environment, with multiple sources such as food and
beverages, industrial effluents, cigarette smoke, and additives. The toxic effects of exposure …

Highlights•Naringin induced a marked decrease of renal injury markers in MTX-treated
rats.•Naringin protected against redox imbalance of renal tissue in MTX-treated …

Reactive carbonyl species (RCS) formed by lipidperoxidation as free forms or as enzymatic
and non-enzymatic conjugates are widely used as an index of oxidative stress. Besides …

Chronic kidney disease (CKD) can be considered as a clinical model for premature aging.
However, non-invasive biomarkers to detect early kidney damage and the onset of a …

Inflammasomes are multiprotein platforms responsible for the release of pro-inflammatory
cytokines interleukin (IL)-1β and IL-18. Mouse studies have identified inflammasome …

Necrotizing enterocolitis (NEC) is a neonatal intestinal disease associated with oxidative
stress. The targets of peroxidation and the role of the innate intestinal epithelial antioxidant …

Previous studies have shown mitochondrial dysfunction in various acute kidney injuries and
chronic kidney diseases. Lipoic acid exerts potent effects on oxidant stress and modulation …

Anthracyclines are essential adjuvant therapies for a variety of cancers, particularly breast,
gastric and esophageal cancers. Whilst prolonging cancer-related survival, these agents …

Atherosclerosis is a chronic inflammatory vascular disease that is characterized by the
accumulation of lipids and immune cells in plaques built up inside artery walls …