Calcium signalling has long been implicated in bipolar disorder, especially by reports of
altered intracellular calcium ion concentrations ([Ca2+]). However, the evidence has not …

Bipolar disorder (BD) is a chronic psychiatric illness described by severe changes in mood.
Extensive research has been carried out to understand the aetiology and pathophysiology of …

We performed the oligonucleotide microarray analysis in bipolar disorder, major depression,
schizophrenia, and control subjects using postmortem prefrontal cortices provided by the …

The delineation of dopamine dysfunction in the mentally ill has been a long-standing quest
of biological psychiatry. The present study focuses on a recently recognized group of …

Background: Human bipolar illness is characterized by mood state‐and diagnosis‐
associated abnormalities of cellular cation distribution and transport. These include reduced …

Background There is an emerging interest in the use of cellular models to study psychiatric
disorders. We have systematically reviewed the application of cellular models to understand …

Bipolar disorder (BD) is one of the major psychiatric diseases in which the impairment of
mitochondrial functions has been closely connected or associated with the disease …

BACKGROUD: Aberrant intracellular calcium (Ca2+) signaling in patients with bipolar-I
disorder (BD-I) suggests disturbed endoplasmic reticulum (ER) function in BD. We examined …

Dissecting trait neurobiological abnormalities in bipolar disorder (BD) from those
characterizing episodes of mood disturbance will help elucidate the aetiopathogenesis of …

Background Bipolar disorder is a heterogeneous mood disorder associated with several
important clinical comorbidities, such as eating disorders. This clinical heterogeneity …