The use of derivatives of natural and synthetic origin has gained attention because of their
therapeutic effects against human diseases. Coumarins are one of the most common …

Esculetin is a natural dihydroxy coumarin; it is mainly extracted from twig skin and the trunk
bark of the Chinese herbal medicine Fraxinus rhynchophylla Hance. Emerging evidence …

Esculetin is a coumarin compound, which belongs to the class of benzopyrone enriched in
various plants such as Sonchus grandifolius, Aesculus turbinata, etc. Free radicals lead to …

Amorphous calcium phosphate nanoparticles (ACP NPs) exhibit excellent biocompatibility
and biodegradability properties. ACP NPs were functionalized with two coumarin …

Coumarin derivates have been proposed as a potential treatment for metabolic-dysfunction-
associated fatty liver disease (MAFLD). However, the mechanisms underlying their …

Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription factor related to stress
response and cellular homeostasis that plays a key role in maintaining the redox system …

Neurodegenerative disorders are characterized by mitochondrial dysfunction and
subsequently oxidative stress, inflammation, and apoptosis that contribute to neuronal …

Chronic exposure to aluminium (Al) can contribute to the progression of several neurological
and neurodegenerative diseases. Al is a metal that promotes oxidative damage leading to …

Cumulative evidence suggests that β-amyloid and oxidative stress are closely related with
each other and play key roles in the process of Alzheimer's disease (AD). Multitarget …

Alzheimer's disease (AD) is a detrimental neurodegenerative disease affecting the elderly.
Clinically, it is characterized by progressive memory decline and subsequent loss of broader …