Abstract The interleukin (IL)-1 family member IL-1α is a ubiquitous and pivotal pro-
inflammatory cytokine. The IL-1α precursor is constitutively present in nearly all cell types in …

The members of the Management and Therapy Subcommittee undertook an evidence-
based review of current dry eye therapies and management options. Management options …

Sjögren syndrome (SjS) is a systemic autoimmune disease that primarily affects the exocrine
glands (mainly the salivary and lacrimal glands) and results in the severe dryness of …

In the field of predictive, preventive and personalised medicine, researchers are keen to
identify novel and reliable ways to predict and diagnose disease, as well as to monitor …

Personalized and point-of-care (POC) diagnoses are critical for ocular physiology and
disease diagnosis. Real-time monitoring and continuous sampling abilities of tear fluid and …

Dry eye disease (DED) is a commonly occurring, multifactorial disease characterized by
reduced tear film stability and hyperosmolarity at the ocular surface, leading to discomfort …

The human tear film is a 3‐layered coating of the surface of the eye and a loss, or reduction,
in any layer of this film may result in a syndrome of blurry vision and burning pain of the eyes …

Exosomes, nanosized extracellular vesicles of 30–150 nm, are shed by almost all cell types.
Bearing proteins, lipids, RNAs, and DNAs, exosomes have emerged as vital biological …

Purpose: This review represents the current in vitro, in vivo animal and human researches
on the roles of IL-6 in inflammatory ocular disorders. Data sources were literature reviewed …

Investigating cytokines in tear fluid and saliva may offer valuable information for
understanding the pathogenesis of primary Sjögren's syndrome (pSS). Cytokine profiles in …