Cellular and molecular immune response to chikungunya virus infection

ISB Tanabe, ELL Tanabe, EC Santos… - Frontiers in cellular …, 2018 - frontiersin.org
Chikungunya virus (CHIKV) is a re-emergent arthropod-borne virus (arbovirus) that causes a
disease characterized primarily by fever, rash and severe persistent polyarthralgia. In the …

Understanding COVID-19 via comparative analysis of dark proteomes of SARS-CoV-2, human SARS and bat SARS-like coronaviruses

R Giri, T Bhardwaj, M Shegane, BR Gehi… - Cellular and Molecular …, 2021 - Springer
The recently emerged coronavirus designated as SARS-CoV-2 (also known as 2019 novel
coronavirus (2019-nCoV) or Wuhan coronavirus) is a causative agent of coronavirus …

Recent advances in the role of different nanoparticles in the various biosensors for the detection of the chikungunya virus

SA Shahrtash, ZS Ghnim, M Ghaheri, J Adabi… - Molecular …, 2024 - Springer
Humans contract the Chikungunya virus (CHIKV), an alphavirus transmitted by mosquitoes
that induces acute and chronic musculoskeletal discomfort and fever. Millions of cases of the …

Development of a U-bent plastic optical fiber biosensor with plasmonic labels for the detection of chikungunya non-structural protein 3

A George, MS Amrutha, P Srivastava, S Sunil, VVR Sai… - Analyst, 2021 - pubs.rsc.org
This study presents a novel plasmonic fiber optic sandwich immunobiosensor for the
detection of chikungunya, an infectious mosquito-borne disease with chronic …

Investigating into the molecular interactions of flavonoids targeting NS2B-NS3 protease from ZIKA virus through in-silico approaches

R Yadav, C Selvaraj, M Aarthy, P Kumar… - Journal of …, 2021 - Taylor & Francis
Zika virus (ZIKV), belongs to the flavivirus genus and Flaviviridae family that associated with
serious diseased conditions like microcephaly and other neurological disorders (Guillan …

[HTML][HTML] Zika virus NS4A cytosolic region (residues 1–48) is an intrinsically disordered domain and folds upon binding to lipids

A Kumar, P Kumar, R Giri - Virology, 2020 - Elsevier
In flaviviruses, the NS4A is an integral transmembrane protein that contributes to form virus-
induced membrane curvature. However, structural features of NS4A are not documented in …

Folding and structural polymorphism of p53 C-terminal domain: One peptide with many conformations

A Kumar, P Kumar, S Kumari, VN Uversky… - Archives of biochemistry …, 2020 - Elsevier
Abstracts Proteins of the p53 family are best known for their role in the regulation of cell
cycle. The p53 protein, as a model system, has been extensively explored in numerous …

Understanding the penetrance of intrinsic protein disorder in rotavirus proteome

D Kumar, A Singh, P Kumar, VN Uversky… - International journal of …, 2020 - Elsevier
Rotavirus is a major cause of severe acute gastroenteritis in the infants and young children.
The past decade has evidenced the role of intrinsically disordered proteins/regions …

The dark side of Alzheimer's disease: unstructured biology of proteins from the amyloid cascade signaling pathway

K Gadhave, BR Gehi, P Kumar, B Xue… - Cellular and Molecular …, 2020 - Springer
Alzheimer's disease (AD) is a leading cause of age-related dementia worldwide. Despite
more than a century of intensive research, we are not anywhere near the discovery of a cure …

Roles, characteristics, and analysis of intrinsically disordered proteins: a minireview

F Lermyte - Life, 2020 - mdpi.com
In recent years, there has been a growing understanding that a significant fraction of the
eukaryotic proteome is intrinsically disordered, and that these conformationally dynamic …