The noncanonical pathway for in vivo nitric oxide generation: the nitrate-nitrite-nitric oxide pathway

V Kapil, RS Khambata, DA Jones, K Rathod… - Pharmacological …, 2020 - Elsevier
In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Nitrite and nitrate chemical biology and signalling

AW DeMartino, DB Kim‐Shapiro… - British journal of …, 2019 - Wiley Online Library
Inorganic nitrate (NO3−), nitrite (NO2−) and NO are nitrogenous species with a diverse and
interconnected chemical biology. The formation of NO from nitrate and nitrite via a reductive …

Functional properties of beetroot (Beta vulgaris) in management of cardio-metabolic diseases

P Mirmiran, Z Houshialsadat, Z Gaeini… - Nutrition & …, 2020 - Springer
Red beetroot (Beta vulgaris), as a naturally occurring root vegetable and a rich source of
phytochemicals and bioactive compounds, is known for its beneficial roles in the …

Role of nitric oxide in insulin secretion and glucose metabolism

Z Bahadoran, P Mirmiran, A Ghasemi - Trends in Endocrinology & …, 2020 - cell.com
Nitric oxide (NO) contributes to carbohydrate metabolism and decreased NO bioavailability
is involved in the development of type 2 diabetes mellitus (T2DM). NO donors may improve …

The benefits and risks of beetroot juice consumption: a systematic review

H Zamani, M De Joode, IJ Hossein… - Critical reviews in …, 2021 - Taylor & Francis
Beetroot juice (BRJ) has become increasingly popular amongst athletes aiming to improve
sport performances. BRJ contains high concentrations of nitrate, which can be converted …

[HTML][HTML] Nitric oxide, aging and aerobic exercise: sedentary individuals to Master's athletes

OM Shannon, T Clifford, DR Seals, DH Craighead… - Nitric Oxide, 2022 - Elsevier
Aging is associated with a decline in physiological function and exercise performance.
These effects are mediated, at least in part, by an age-related decrease in the bioavailability …

Vegetable-derived bioactive nitrate and cardiovascular health

CP Bondonno, LC Blekkenhorst, AH Liu… - Molecular Aspects of …, 2018 - Elsevier
Vegetable derived nitrate is now recognised as an important bioactive phytochemical with
cardioprotective properties. Nitrate, through the recently described enterosalivary nitrate …

[HTML][HTML] Nitrate, the oral microbiome, and cardiovascular health: a systematic literature review of human and animal studies

LC Blekkenhorst, NP Bondonno, AH Liu… - The American journal of …, 2018 - Elsevier
Background Dietary nitrate is an important source of nitric oxide (NO), a molecule critical for
cardiovascular health. Nitrate is sequentially reduced to NO through an enterosalivary …

[HTML][HTML] Beetroot for managing diabetes and its associated gut dysbiosis: Current findings and challenges

EBM Daliri, D Baltriukienė, A Burokas - Trends in Food Science & …, 2023 - Elsevier
There is strong evidence that diabetes is closely linked with gut dysbiosis such that insults to
the gut microbiota can lead to diabetes. Meanwhile, since diabetes can be caused by a …

Performance and health benefits of dietary nitrate supplementation in older adults: A systematic review

L Stanaway, K Rutherfurd-Markwick, R Page, A Ali - Nutrients, 2017 - mdpi.com
Supplementation with nitrate (NO3−)-rich beetroot juice has been shown to improve
exercise performance and cardiovascular (CV) responses, due to an increased nitric oxide …