Cancer remains the leading cause of death worldwide despite advances in treatment
options for patients. As such, safe and effective therapeutics are required. Short peptides …

Antimicrobial peptides (AMPs) are an interesting class of antibiotics characterized by their
unique antibiotic activity and lower propensity for developing resistance compared to …

The first report in literature of the isolation of coumarin was in the year 1820. After this report,
other papers were published demonstrating the isolation and synthesis of coumarin and …

Hybrid molecules, furnished by combining two or more pharmacophores is an emerging
concept in the field of medicinal chemistry and drug discovery that has attracted substantial …

Hybridization is emerged as a promising strategy in the discovery of new drugs, especially
these with complimentary activities and multiple pharmacological targets that are the …

Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally
diverse molecules are produced as the first line of defense against pathogens such as …

In recent years, the increase of invasive fungal infections and the emergence of antifungal
resistance stressed the need for new antifungal drugs. Peptides have shown to be good …

A library of seventeen novel 1, 2, 3-triazole derivatives were efficiently synthesized in
excellent yields by the popular 'click chemistry'approach and evaluated in vitro for their anti …

A series of coumarin appended triazole hybrids of biotic interest was synthesized through
click chemistry approach from the coumarin based terminal alkynes and aromatic azides. All …

Ratiometric fluorescent probes allow the simultaneous measurement of two fluorescence
signals at different wavelengths followed by calculation of their intensity ratio, which can …