Adding Fuel to the Fire? The Skin Microbiome in Atopic Dermatitis

SS Kashaf, HH Kong - Journal of Investigative Dermatology, 2024 - Elsevier
Atopic dermatitis (AD) is a multifactorial, heterogeneous disease characterized by epidermal
barrier dysfunction, immune system dysregulation, and skin microbiome alterations. Skin …

Atopic dermatitis and psoriasis: similarities and differences in metabolism and microbiome

Y Chen, C Peng, L Zhu, J Wang, Q Cao… - Clinical Reviews in …, 2024 - Springer
Atopic dermatitis and psoriasis are common chronic inflammatory diseases of high
incidence that share some clinical features, including symptoms of pruritus and pain, scaly …

Multi-omics signatures reveal genomic and functional heterogeneity of Cutibacterium acnes in normal and diseased skin

T Yu, X Xu, Y Liu, X Wang, S Wu, Z Qiu, X Liu, X Pan… - Cell Host & Microbe, 2024 - cell.com
Cutibacterium acnes is the most abundant bacterium of the human skin microbiome since
adolescence, participating in both skin homeostasis and diseases. Here, we demonstrate …

Probiotics and Prebiotics Orally Assumed as Disease Modifiers for Stable Mild Atopic Dermatitis: An Italian Real-Life, Multicenter, Retrospective, Observational Study

D Colombo, C Rigoni, A Cantù, A Carnevali, R Filippetti… - Medicina, 2023 - mdpi.com
The role of the skin–gut axis in atopic dermatitis (AD) remains a subject of debate, limiting
non-pharmacological interventions such as probiotics and prebiotics. To improve …

Patho‐immunological mechanisms of atopic dermatitis: The role of the three major human microbiomes

Z Zhou, J Yang, Q Liu, J Gao… - Scandinavian Journal of …, 2024 - Wiley Online Library
Atopic dermatitis (AD) is a genetically predisposed allergic inflammatory dermatosis with
chronic, pruritic, and recurrent features. Patients with AD have dry and itchy skin, often …

Skin microbiota: pathogenic roles and implications in atopic dermatitis

C Huang, F Zhuo, Y Guo, S Wang, K Zhang… - Frontiers in Cellular …, 2025 - frontiersin.org
Atopic dermatitis (AD) is a chronic and inflammatory skin disorder characterized by impaired
barrier function and imbalanced immunity. Recent advances have revealed that dysbiosis of …

An Observational Study: Association Between Atopic Dermatitis and Bacterial Colony of the Skin Based on 16S rRNA Gene Sequencing

XP Yang, YY Liu, CY Zhang, KK Huang… - Clinical, Cosmetic …, 2024 - Taylor & Francis
Aim Atopic dermatitis (AD) often accompanies skin infections, and bacterial skin infections
often cause persistent and worsening symptoms. In this study, we explored the key changes …

Nasal, dermal, oral and indoor dust microbe and their interrelationship in children with allergic rhinitis

H Tang, S Du, Z Niu, D Zhang, Z Tang, H Chen… - BMC microbiology, 2024 - Springer
Background Allergic rhinitis (AR) subjects might have their microenvironment changed due
to pathogenesis and living environment. Whether the nasal microbe in AR children differs …

The Role of the Microbiota in the Pathogenesis and Treatment of Atopic Dermatitis—A Literature Review

M Wrześniewska, J Wołoszczak, G Świrkosz… - International Journal of …, 2024 - mdpi.com
Atopic dermatitis (AD) is a chronic inflammatory skin condition with a high prevalence
worldwide. AD pathogenesis is complex and consists of immune system dysregulation and …

Staphylococcus aureus Proteases: Orchestrators of Skin Inflammation

SN Kline, Y Saito, NK Archer - DNA and Cell Biology, 2024 - liebertpub.com
Skin homeostasis relies on a delicate balance between host proteases and protease
inhibitors along with those secreted from microbial communities, as disruption to this …