The interior of a living cell is a crowded, heterogenuous, fluctuating environment. Hence, a major challenge in modeling intracellular transport is to analyze stochastic processes within …
One of the major challenges in modern biology is to understand how the molecular components of a living cell operate in a highly noisy environment. What are the specific …
The dynamics of constituents and the surface response of cellular membranes—also in connection to the binding of various particles and macromolecules to the membrane—are …
We present a general theory which allows one to accurately evaluate the mean first-passage time (FPT) for regular random walks in bounded domains, and its extensions to related first …
D Normanno, L Boudarène, C Dugast-Darzacq… - Nature …, 2015 - nature.com
Many cellular functions rely on DNA-binding proteins finding and associating to specific sites in the genome. Yet the mechanisms underlying the target search remain poorly understood …
A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors “transduce” input energy into …
PC Bressloff - Journal of Physics A: Mathematical and …, 2017 - iopscience.iop.org
There has been a resurgence of interest in non-equilibrium stochastic processes in recent years, driven in part by the observation that the number of molecules (genes, mRNA …
Stochastic resetting, a diffusive process whose amplitude is reset to the origin at random times, is a vividly studied strategy to optimize encounter dynamics, eg, in chemical reactions …
Following recent discoveries of colocalization of downstream-regulating genes in living cells, the impact of the spatial distance between such genes on the kinetics of gene product …