In the last decade, extensive research has emerged into understanding the impact of risk
factors for Alzheimer's Disease (AD) on brain in pre-symptomatic stages. We investigated …

Microbes have been suspected to cause Alzheimer's disease since at least 1908, but this
has generally remained unpopular in comparison to the amyloid hypothesis and the …

The major genetic risk factor for Alzheimer's disease (AD), APOE4, accelerates beta-amyloid
(Aβ) plaque formation, but whether this is caused by APOE expressed in microglia or …

Determining the structure‐function relationships of protein aggregates is a fundamental
challenge in biology. These aggregates, whether formed in vitro, within cells, or in living …

Aims Alzheimer's disease (AD) is characterized by β-amyloid (Aβ) aggregation and
neuroinflammation, leading to progressive synaptic loss and cognitive decline. Recent …

Despite advances in biomedicine, therapies that prevent neuronal loss have not been
effective. Several strategies targeting the defining markers of the main neurodegenerative …

The aggregation of Aβ42 into misfolded oligomers is a central event in the pathogenesis of
Alzheimer's disease. In this study, we aimed to develop a robust experimental system that …

Alzheimer's disease (AD) is the leading cause of dementia worldwide, and predominantly
affects elderly populations. This disease is well known for its effects on the brain, but a …

The aggregation of Aβ42 into misfolded oligomers is a central event in the pathogenesis of
Alzheimer's disease. To study this process, we developed a robust experimental system that …