The nuclear pore complex: birth, life, and death of a cellular behemoth
Nuclear pore complexes (NPCs) are the only transport channels that cross the nuclear
envelope. Constructed from~ 500–1000 nucleoporin proteins each, they are among the …
envelope. Constructed from~ 500–1000 nucleoporin proteins each, they are among the …
Nuclear transport proteins: Structure, function, and disease relevance
Y Yang, L Guo, L Chen, B Gong, D Jia… - Signal Transduction and …, 2023 - nature.com
Proper subcellular localization is crucial for the functioning of biomacromolecules, including
proteins and RNAs. Nuclear transport is a fundamental cellular process that regulates the …
proteins and RNAs. Nuclear transport is a fundamental cellular process that regulates the …
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex
INTRODUCTION The nuclear pore complex (NPC) resides on the nuclear envelope (NE)
and mediates nucleocytoplasmic cargo transport. As one of the largest cellular machineries …
and mediates nucleocytoplasmic cargo transport. As one of the largest cellular machineries …
Implications of a multiscale structure of the yeast nuclear pore complex
CW Akey, I Echeverria, C Ouch, I Nudelman, Y Shi… - Molecular Cell, 2023 - cell.com
Nuclear pore complexes (NPCs) direct the nucleocytoplasmic transport of macromolecules.
Here, we provide a composite multiscale structure of the yeast NPC, based on improved 3D …
Here, we provide a composite multiscale structure of the yeast NPC, based on improved 3D …
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data
ContinuousFlex is a user-friendly open-source software package for analyzing continuous
conformational variability of macromolecules in cryo electron microscopy (cryo-EM) and cryo …
conformational variability of macromolecules in cryo electron microscopy (cryo-EM) and cryo …
Nuclear export of pre-60S particles through the nuclear pore complex
Z Li, S Chen, L Zhao, G Huang, H Xu, X Yang, P Wang… - Nature, 2023 - nature.com
The nuclear pore complex (NPC) is the bidirectional gate that mediates the exchange of
macromolecules or their assemblies between nucleus and cytoplasm,–. The assembly …
macromolecules or their assemblies between nucleus and cytoplasm,–. The assembly …
Regulatory dynamics of the higher-plant PSI–LHCI supercomplex during state transitions
J Wu, S Chen, C Wang, W Lin, C Huang, C Fan, D Han… - Molecular Plant, 2023 - cell.com
State transition is a fundamental light acclimation mechanism of photosynthetic organisms in
response to the environmental light conditions. This process rebalances the excitation …
response to the environmental light conditions. This process rebalances the excitation …
Structure of the nuclear pore complex goes atomic
The nuclear pore complex (NPC) is a supra-molecular assembly that mediates substance
and information flow across the nuclear envelope (NE). Due to its extraordinary size and …
and information flow across the nuclear envelope (NE). Due to its extraordinary size and …
Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex
Nuclear pore complex (NPC) mediates nucleocytoplasmic shuttling. Here we present single-
particle cryo-electron microscopy structure of the inner ring (IR) subunit from the Xenopus …
particle cryo-electron microscopy structure of the inner ring (IR) subunit from the Xenopus …
[HTML][HTML] Cryo-electron microscopy reveals the structure of the nuclear pore complex
L Tai, G Yin, F Sun, Y Zhu - Journal of Molecular Biology, 2023 - Elsevier
The nuclear pore complex (NPC) is a giant protein assembly that penetrates the double
layers of the nuclear membrane. The overall structure of the NPC has approximately …
layers of the nuclear membrane. The overall structure of the NPC has approximately …