Percolation and synchronization are two phase transitions that have been extensively
studied since already long ago. A classic result is that, in the vast majority of cases, these …

The emergence of large-scale connectivity and synchronization are crucial to the structure,
function and failure of many complex socio-technical networks. Thus, there is great interest …

Sleep is conserved from invertebrates to vertebrates, and is tightly regulated in a
homeostatic manner. The molecular and cellular mechanisms that determine the amount of …

The purpose of this white paper is to provide a succinct summary of the different
experimental approaches that have been used in preclinical post-operative cognitive …

The needs fulfilled by sleep are unknown, though the effects of insufficient sleep are
manifold. To better understand how the need to sleep is sensed and discharged, much effort …

Despite decades of intense study, the functions of sleep are still shrouded in mystery. The
difficulty in understanding these functions can be at least partly attributed to the varied …

Cell excitability and its modulation by hormones and neurotransmitters involve the concerted
action of a large repertoire of membrane proteins, especially ion channels. Unique …

Circadian clocks regulate membrane excitability in master pacemaker neurons to control
daily rhythms of sleep and wake. Here, we find that two distinctly timed electrical drives …

General anesthesia serves a critically important function in the clinical care of human
patients. However, the anesthetized state has foundational implications for biology because …

Consciousness requires a dynamic balance of integration and segregation in brain
networks. We report an fMRI-based metric, the integration-segregation difference (ISD) …