the CD5 B cell

TJ Kipps - Advances in immunology, 1989 - Elsevier
Publisher Summary The international nomenclature established for cell differentiation
antigens will be used. Historically, the CD5 B cell in mice or humans has been referred to as …

Rheumatoid factor and immune networks.

DA Carson, PP Chen, RI Fox, TJ Kipps… - Annual review of …, 1987 - europepmc.org
Rheumatoid factors represent a normal component of the immune network. The
autoantibodies promote complement fixation and clearance of immune complexes. They …

Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B …

MJ Shlomchik, DA Nemazee, VL Sato… - The Journal of …, 1986 - rupress.org
The nucleotide sequences of heavy and light chains from 10 monoclonal IgM anti-IgG1 (RF)
antibodies were determined and reported here as translated amino acid sequences. Only …

High-frequency expression of a conserved kappa light-chain variable-region gene in chronic lymphocytic leukemia.

TJ Kipps, S Fong, E Tomhave… - Proceedings of the …, 1987 - National Acad Sciences
Malignant B lymphocytes from several patients with chronic lymphocytic leukemia (CLL)
were examined for reactivity with murine monoclonal antibody 17.109. This antibody …

Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.

GJ Silverman, RD Goldfien, P Chen… - The Journal of …, 1988 - Am Soc Clin Investig
Rheumatoid factors (RFs) in humans have been studied intensively because of their
association with autoimmune and lymphoproliferative diseases. Many human IgM-RFs …

The neuropathy of plasma cell dyscrasia: binding of IgM M‐proteins to peripheral nerve glycolipids

L Freddo, T Ariga, M Saito, LC Macala, RK Yu, N Latov - Neurology, 1985 - AAN Enterprises
In some patients with neuropathy and plasma cell dyscrasia, the M-proteins bind to
peripheral nerves. Binding of M-proteins to peripheral nerve glycolipids was examined by …

Rheumatoid factor

PP Chen, S Fong, DA Carson - Rheumatic Disease Clinics of North …, 1987 - Elsevier
Many human RF-associated crossreactive idiotypes (CRIs) have been defined. Since these
CRIs probably are the phenotypic markers of Ig variable region genes, the data suggest that …

Genetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies.

PP Chen, K Albrandt, NK Orida… - Proceedings of the …, 1986 - National Acad Sciences
The role of immunoglobulin structural genes in the generation of autoantibodies in humans
has not been elucidated. Human monoclonal IgM anti-IgG autoantibodies (rheumatoid …

Isolation and characterization of a light chain variable region gene for human rheumatoid factors.

PP Chen, DL Robbins, FR Jirik, TJ Kipps… - The Journal of …, 1987 - rupress.org
Previously, we isolated a Vk gene (Humkv325) from a human placenta that encodes RF light
chains bearing the PSL2 and PSL3 CRI markers. Here we report the isolation and …

[HTML][HTML] Light chains of immunoglobulins: structural-genetic correlates

A Solomon - Blood, 1986 - Elsevier
WITHIN the past decade, studies by molecular geneticists on the composition and
organization of immunoglobulin (Ig)-coding genes at the DNA level have vastly increased …