Human papillomaviruses (HPVs) have evolved over millions of years to propagate
themselves in a range of different animal species including humans. Viruses that have co …

An association between human papillomavirus (HPV) infection and the development of
cervical cancer was initially reported over 30 years ago, and today there is overwhelming …

E7 is an accessory protein that is not encoded by all papillomaviruses. The E7 amino
terminus contains two regions of similarity to conserved regions 1 and 2 of the adenovirus …

Human papillomaviruses (HPV) are the etiological agents of cervical and other anogenital
malignancies. Over 100 different types of HPVs have been identified to date, and all target …

Infection with HPV starts with the access of the viral particles to basal cells in the epidermis,
potentially via microtraumas to the skin. The basal cells are able to keep away these …

Human papillomaviruses (HPVs) are the causative agents of 5% of all human cancers, with
cervical cancer being the most important. Two viral oncoproteins, E6 and E7, are essential …

Infectious etiologies for certain human cancers have long been suggested by
epidemiological studies and studies with experimental animals. Important support for this …

Human papillomaviruses (HPVs) are small double‐stranded DNA viruses that infect the
cutaneous and mucosal epithelium. Infection by specific HPV types has been linked to the …

Cyclin-dependent kinases (CDKs) regulate the cell division cycle, apoptosis, transcription
and differentiation in addition to functions in the nervous system. Deregulation of CDKs in …

Cell division cycle 25 A (Cdc25A), a dual-specificity protein phosphatase, is one of the most
crucial cell cycle regulators, which removes the inhibitory phosphorylation in cyclin …