Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage
degradation but also synovial membrane inflammation, osteophyte formation and …

In mature individuals, hyaline cartilage demonstrates a poor intrinsic capacity for repair, thus
even minor defects could result in progressive degeneration, impeding quality of life …

Cartilage equivalents from hydrogels containing chondrocytes exhibit excellent potential in
hyaline cartilage regeneration, yet current approaches have limited success at reconstituting …

Focal articular cartilage (AC) defects, if left untreated, can lead to debilitating diseases such
as osteoarthritis. While several tissue engineering strategies have been developed to …

Osteochondral defects are most commonly characterized by damages to both cartilage and
bone tissues as a result of serious traumas or physical diseases; because these two tissues …

Mesenchymal stem cells (MSCs) are potential candidates in cell-based therapy for cartilage
repair and regeneration. However, during chondrogenic differentiation, MSCs undergo …

In the current study, a novel nanocomposite hydrogel scaffold comprising of natural-based
gelatin and synthetic-based (poly D, L (lactide-co-glycolide)-b-poly (ethylene glycol)-b-poly …

Cartilage injuries and bone loss become increasingly prevalent in modern societies.
Articular cartilage and menisci have low or no capacity for self-repair and none of the …

While matrix-assisted autologous chondrocyte implantation has emerged as a promising
therapy to treat focal chondral defects, matrices that support regeneration of hyaline …

There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost
effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and …