Growth hormone (GH) is an important modulator of insulin sensitivity. Multiple mechanisms
appear to be involved in this modulatory effect. GH does not interact directly with the insulin …

JLE - Magnesium Research - The biochemical function of Mg 2+ in insulin secretion, insulin
signal transduction and insulin resistance JLE Home Bookstore Search for books Collections …

Insulin resistance is a cardinal feature of normal pregnancy and excess growth hormone
(GH) states, but its underlying mechanism remains enigmatic. We previously found a …

The insulin receptor substrates function at the heart of the insulin signalling network. It has
recently become apparent that the intracellular localisation of these molecules is regulated …

Growth hormone (GH) counteracts insulin action on lipid and glucose metabolism. However,
the sequence of molecular events leading to these changes is poorly understood. Insulin …

Recently, single chain peptides have been designed that target the insulin receptor and
mimic insulin action. The aim of this study is to explore if activation of the insulin receptor …

We recently demonstrated that epinephrine could inhibit the activation by insulin of insulin
receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase (PI3-kinase) in …

GH stimulates the tyrosine phosphorylation of various cellular polypeptides, including the
GH receptor itself, in an early part of the intracellular response. Some of these …

Objective Untreated GH‐deficient adults are predisposed to insulin resistance and excess
cardiovascular mortality. We showed previously that short‐term treatment with a very low GH …

Altered insulin secretion and sensitivity have been observed in Mg-deficient animals.
However, the effects of Mg deficiency and supplementation on intracellular signaling events …