[HTML][HTML] Cortical-bone fragility—insights from sFRP4 deficiency in Pyle's disease
Background Cortical-bone fragility is a common feature in osteoporosis that is linked to
nonvertebral fractures. Regulation of cortical-bone homeostasis has proved elusive. The …
nonvertebral fractures. Regulation of cortical-bone homeostasis has proved elusive. The …
Sclerosing bone dysplasias: leads toward novel osteoporosis treatments
I Fijalkowski, E Boudin, G Mortier, W Van Hul - Current osteoporosis …, 2014 - Springer
Sclerosing bone dysplasias are a group of rare, monogenic disorders characterized by
increased bone density resulting from the disturbance in the fragile equilibrium between …
increased bone density resulting from the disturbance in the fragile equilibrium between …
Genetic Screening of WNT4 and WNT5B in Two Populations with Deviating Bone Mineral Densities
G Hendrickx, E Boudin, E Steenackers… - Calcified tissue …, 2017 - Springer
A role for WNT4 and WNT5B in bone metabolism was indicated by genome-wide
association studies (GWAS) and a Wnt4 knockout mouse model. The aim of this study was …
association studies (GWAS) and a Wnt4 knockout mouse model. The aim of this study was …
No mutations in the serotonin related TPH1 and HTR1B genes in patients with monogenic sclerosing bone disorders
Since the identification of LRP5 as the causative gene for the osteoporosis pseudoglioma
syndrome (OPPG) as well as the high bone mass (HBM) phenotype, LRP5 and the Wnt/β …
syndrome (OPPG) as well as the high bone mass (HBM) phenotype, LRP5 and the Wnt/β …
Single nucleotide variations in the Wnt antagonist sFRP3 (rs7775 & rs288326) and sFRP4 (rs1802073 & 1802074) genes and their association with lung cancer risk in …
Purpose To evaluate the role of genetic variants or single nucleotide polymorphic variants
(rs288326, rs7775, rs1802073 and rs1802074) in Secreted frizzled related protein in …
(rs288326, rs7775, rs1802073 and rs1802074) in Secreted frizzled related protein in …