Highlights•Applications of alternative carriers to lactose in DPIs are reviewed.•Lactose, the
most commonly used carrier in DPI formulations, has some limitations.•These limitations …

Pharmaceutical powders are typically insulators consisting of relatively small particles and
thus they usually exhibit significant electrostatic charging behaviours. In the inhalation field …

Emerging 3D printing technologies offer an exciting opportunity to create customized 3D
objects additively from a digital design file. 3D printing may be further leveraged for …

This paper reports a custom-built binder jet 3D printer for pilot-scale manufacturing of
pharmaceutical tablets. The printer is equipped with high-throughput piezoelectric inkjet …

The purpose of this study was to evaluate the effect of carrier particle size on properties of
dry powder and its effect on dry powder inhaler (DPI) performance. Commercial α-lactose …

Solid lipid nanoparticles (SLN) containing rifabutin (RFB), with pulmonary administration
purposes, were developed through a technique that avoids the use of organic solvents or …

Inhalation therapy has strong history of more than 4000 years and it is well recognized
around the globe within every culture. In early days, inhalation therapy was designed for …

The aim of this study was to characterise the aerosolisation properties of salbutamol
sulphate (SS) from dry powder inhaler (DPI) formulations containing different carrier …

In the current study electrospraying methodology was used for particle engineering of
montelukast and budesonide to prepare a combined inhalable dry powder formulation …

The purpose of this study was to evaluate the relationships between physicochemical
properties and aerosolisation performance of different grades of lactose. In order to get a …