The effects of heavy metals on human metabolism

Z Fu, S Xi - Toxicology mechanisms and methods, 2020 - Taylor & Francis
As technology continues to advance, heavy metals in drinking water have exceeded
recommended limits from regulators around the world. The main source of human exposure …

1, 3, 5‐Triazine: A versatile pharmacophore with diverse biological activities

S Singh, MK Mandal, A Masih, A Saha… - Archiv der …, 2021 - Wiley Online Library
Triazine and its derivatives have been the epicenter of chemotherapeutic molecules due to
their effective biological activities, such as antibacterial, fungicidal, antimalarial, anticancer …

Phenolic compounds as antioxidants: carbonic anhydrase isoenzymes inhibitors

I Gulcin, S Beydemir - Mini reviews in medicinal chemistry, 2013 - ingentaconnect.com
Antioxidant compounds can scavenge free radicals and increase shelf life by retarding the
process of lipid peroxidation, which is one of the major reasons for deterioration of food …

In vitro inhibition of α-carbonic anhydrase isozymes by some phenolic compounds

SBÖ Sarikaya, F Topal, M Şentürk, I Gülçin… - Bioorganic & medicinal …, 2011 - Elsevier
Carbonic anhydrase inhibitors (CAIs) are a class of pharmaceuticals used as antiglaucoma
agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and …

In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II

E Bayram, M Senturk, OI Kufrevioglu… - Bioorganic & medicinal …, 2008 - Elsevier
The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2. 1.1) isozymes, hCA
I and II, with a series of salicylic acid derivatives was investigated by using the esterase …

Purification and characterization of the carbonic anhydrase enzyme from horse mackerel (Trachurus trachurus) muscle and the impact of some metal ions and …

C Caglayan, P Taslimi, C Türk, FM Kandemir… - … and Physiology Part C …, 2019 - Elsevier
In this paper, the total carbonic anhydrase (CA) enzyme was purified from horse mackerel
(Trachurus trachurus) muscle with a specific activity of 23,063.93 EU/mg, purification fold of …

Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.

M Sentürk, I Gülçin, A Daştan… - … & medicinal chemistry, 2009 - europepmc.org
The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2. 1.1) isozymes I and
II, with a series of phenol derivatives was investigated by using the esterase assay, with 4 …

Mercury chloride toxicity in human erythrocytes: enhanced generation of ROS and RNS, hemoglobin oxidation, impaired antioxidant power, and inhibition of plasma …

S Ahmad, R Mahmood - Environmental Science and Pollution Research, 2019 - Springer
Mercury is among the most toxic heavy metals and a widespread environmental pollutant.
Mercury chloride (HgCl 2) is an inorganic compound of mercury which is easily absorbed in …

[HTML][HTML] The complex relationship between metals and carbonic anhydrase: new insights and perspectives

MG Lionetto, R Caricato, ME Giordano… - International Journal of …, 2016 - mdpi.com
Carbonic anhydrase is a ubiquitous metalloenzyme, which catalyzes the reversible
hydration of CO2 to HCO3− and H+. Metals play a key role in the bioactivity of this …

In Vitro Inhibition of Human Carbonic Anhydrase I and II Isozymes with Natural Phenolic Compounds

M Şentürk, İ Gülçin, Ş Beydemir… - Chemical biology & …, 2011 - Wiley Online Library
Inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2. 1.1) isozymes I and II
with some natural phenolic derivatives was investigated using the esterase assay with 4 …