Indoles in multicomponent processes (MCPs)

M Shiri - Chemical reviews, 2012 - ACS Publications
In the last two or three decades the emphasis on and applications of green chemical
principles, introduced some significant advances in organic synthesis, such as combinatorial …

2‐Propargyl Alcohols in Organic Synthesis

H Qian, D Huang, Y Bi, G Yan - Advanced Synthesis & Catalysis, 2019 - Wiley Online Library
Propargyl alcohols are widely used in organic reactions. Their great success is rooted in the
presence of multiple functional groups. This review will focus on six types of mechanisms:(i) …

Tandem annulations of propargylic alcohols to indole derivatives

XY Liu, YL Liu, L Chen - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
Indole derivatives are important heterocycles in organic synthesis for serving as privileged
building blocks for functional material and as key components in a lot of bioactive …

Iodine/Oxone® oxidative system for the synthesis of selenylindoles bearing a benzenesulfonamide moiety as carbonic anhydrase I, II, IX, and XII inhibitors

M Palomba, A Angeli, R Galdini… - Organic & …, 2024 - pubs.rsc.org
A wide range of 3-selenylindoles were synthesized via an eco-friendly approach that uses
Oxone® as the oxidant in the presence of a catalytic amount of iodine. This mild and …

Iodocyclization of propargyl alcohols: Highly facile approach to hetero/carbocyclic iodides

T Khan, S Yaragorla - European Journal of Organic Chemistry, 2019 - Wiley Online Library
Iodocyclization of propargyl alcohols is an active area for the construction of
hetero/carbocyclic iodides. Ambiphilic reactivity of propargyl alcohols made it more attractive …

Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand

SN Mistry, J Shonberg, CJ Draper-Joyce… - Journal of medicinal …, 2015 - ACS Publications
Recently, we have demonstrated that N-((trans)-4-(2-(7-cyano-3, 4-dihydroisoquinolin-2 (1
H)-yl) ethyl) cyclohexyl)-1 H-indole-2-carboxamide (SB269652)(1) adopts a bitopic pose at …

Iodine-Mediated Intramolecular Electrophilic Aromatic Cyclization in Allylamines: A General Route to Synthesis of Quinolines, Pyrazolo [4, 3-b] pyridines, and Thieno …

H Batchu, S Bhattacharyya, S Batra - Organic letters, 2012 - ACS Publications
Iodine-Mediated Intramolecular Electrophilic Aromatic Cyclization in Allylamines: A General
Route to Synthesis of Quinolines, Pyrazolo[4,3-b]pyridines, and Thieno[3,2-b]pyridines | Organic …

Cascade intermolecular Michael addition–intramolecular azide/internal alkyne 1, 3-dipolar cycloaddition reaction in one pot

RK Arigela, AK Mandadapu, SK Sharma, B Kumar… - Organic …, 2012 - ACS Publications
A rapid one-pot protocol for the synthesis of indole-based polyheterocycles via a sequential
Lewis acid catalyzed intermolecular Michael addition and an intramolecular azide/internal …

Recent advances in the synthesis of iodoheterocycles via iodocyclization of functionalized alkynes

B Gabriele, R Mancuso… - Current Organic Chemistry, 2014 - benthamdirect.com
Iodocyclization reactions are acquiring an increasing importance in organic synthesis, in
view of the possibility to obtain iodine-containing heterocycles starting from readily available …

Efficient Synthesis of Unsaturated δ‐ and ε‐Lactones/Lactams by Catalytic Cycloisomerization: When Pt Outperforms Pd

D Ke, NÁ Espinosa, S Mallet‐Ladeira… - Advanced Synthesis …, 2016 - Wiley Online Library
Platinum pincer complexes featuring an SCS indenediide backbone have been prepared
and evaluated in the catalytic cycloisomerization of alkynoic acids and N‐tosyl …