The influence of human immunodeficiency virus-1 on hematopoiesis

A Moses, J Nelson, GC Bagby Jr - Blood, The Journal of the …, 1998 - ashpublications.org
THROMBOCYTOPENIA, anemia, lymphocytopenia, mono-cytopenia, and neutropenia and
permutations of these abnormalities are found in most patients with acquired …

Hematologic complications of human immunodeficiency virus infection and the acquired immunodeficiency syndrome

TE Coyle - Medical Clinics, 1997 - medical.theclinics.com
Hematologic abnormalities are among the most common manifestations of advanced human
immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) …

Research article (new england journal of medicine) severe anemia in malawian children

JCJ Calis, KS Phiri, EB Faragher, BJ Brabin… - Malawi Medical …, 2016 - ajol.info
Background: Severe anemia is a major cause of sickness and death in African children, yet
the causes of anemia in this population have been inadequately studied. Methods: We …

Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated …

P Mirandola, C Ponti, G Gobbi, I Sponzilli… - Blood, 2004 - ashpublications.org
The expression of tumor necrosis factor (TNF)–related apoptosis-inducing ligand (TRAIL)
and TRAIL receptors was investigated in resting and cytokine-activated purified primary …

T helper type 1/T helper type 2 cytokines and T cell death: preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of …

J Estaquier, T Idziorek, W Zou, D Emilie… - The Journal of …, 1995 - rupress.org
Human immunodeficiency virus (HIV) infection leads to a progressive loss of CD4+ T helper
(Th) type 1 cell-mediated immunity that is associated with defective in vitro CD4+ T cell …

Structural insights into hydroxycoumarin-induced apoptosis in U-937 cells

ME Riveiro, A Moglioni, R Vazquez, N Gomez… - Bioorganic & medicinal …, 2008 - Elsevier
In the present study, we sought to establish the effect of diverse structural-related
hydroxycoumarins on the proliferation, cytotoxicity, and induction of apoptosis in …

HIV-1 infection of bone marrow hematopoietic progenitor cells and their role in trafficking and viral dissemination

A Alexaki, B Wigdahl - PLoS pathogens, 2008 - journals.plos.org
Patients with HIV-1 often present with a wide range of hematopoietic abnormalities, some of
which may be due to the presence of opportunistic infections and to therapeutic drug …

Filgrastim prevents severe neutropenia and reduces infective morbidity in patients with advanced HIV infection: results of a randomized, multicenter, controlled trial

DR Kuritzkes, D Parenti, DJ Ward, A Rachlis, RJ Wong… - Aids, 1998 - journals.lww.com
Objective: To assess the effect of filgrastim treatment on the incidence of severe neutropenia
in patients with advanced HIV infection, and the effect of initial filgrastim treatment on …

Human Immunodeficiency Virus Type 1 Nef Protein Sensitizes CD4+ T Lymphoid Cells to Apoptosis via Functional Upregulation of the CD95/CD95 Ligand Pathway

G Zauli, D Gibellini, P Secchiero… - Blood, The Journal …, 1999 - ashpublications.org
Many viruses have evolved genes encoding proteins that regulate cell death by apoptosis.
The human immunodeficiency virus type 1 (HIV-1) Nef protein alters T-cell development and …

Tumor necrosis factor–related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent …

P Secchiero, A Gonelli, P Mirandola… - Blood, The Journal …, 2002 - ashpublications.org
Treatment of the human HL-60 cell line with tumor necrosis factor (TNF)–related apoptosis-
inducing ligand (TRAIL) resulted in rapid (6-24 hours) cytotoxicity associated with …