The field of ion mobility-mass spectrometry (IM-MS) has grown with significant momentum in
recent years in both fundamental advances and pioneering applications. A search of the …

Mass spectrometry is a central technology in the life sciences, providing our most
comprehensive account of the molecular inventory of the cell. In parallel with developments …

Mass spectrometry (MS)-based proteomics is emerging as a broadly effective means for
identification, characterization, and quantification of proteins that are integral components of …

The phenomenon of ion mobility (IM), the movement/transport of charged particles under the
influence of an electric field, was first observed in the early 20th Century and harnessed later …

A combined data acquisition and data processing strategy for improving the sensitivity and
resolution of ion mobility measurements is described. This strategy is implemented on a …

Nonsense-mediated mRNA decay (NMD) is a conserved mRNA surveillance pathway that
cells use to ensure the quality of transcripts and to fine-tune transcript abundance. The role …

Highlights•IM–MS coupled to separation techniques is attractive for non-targeted
metabolomics.•CCS values are a complementary molecular descriptor for identification …

Native mass spectrometry (MS) is becoming an important integral part of structural
proteomics and system biology research. The approach holds great promise for elucidating …

Lipids and metabolites are of interest in many clinical and research settings because it is the
metabolome that is increasingly recognized as a more dynamic and sensitive molecular …

The general principles and technical implementations of traditional time-of-flight ion mobility
spectrometers and analyzers with field-dependent mobilities were reviewed in our last …