Incidence, risk factors, and outcomes of venous thromboembolism after oncologic surgery: a systematic review and meta-analysis

M Li, Q Guo, W Hu - Thrombosis research, 2019 - Elsevier
Background The risk and prognosis of VTE associated with oncologic surgery need to be
quantified to guide patient management. We aimed to examine the availability of data and to …

Reciprocal links between venous thromboembolism, coagulation factors and ovarian cancer progression

N Swier, HH Versteeg - Thrombosis research, 2017 - Elsevier
Ovarian cancer is the most lethal gynecological malignancy, which is due to late
presentation. Treating advanced stage ovarian cancer is difficult, and tumor recurrence and …

Safety and efficacy of apixaban vs enoxaparin for preventing postoperative venous thromboembolism in women undergoing surgery for gynecologic malignant …

SR Guntupalli, A Brennecke, K Behbakht… - JAMA network …, 2020 - jamanetwork.com
Importance Current guidelines recommend a 28-day course of enoxaparin for
thromboprophylaxis after surgery for gynecologic cancer. The high cost of this medication …

[HTML][HTML] Podoplanin promotes tumor growth, platelet aggregation, and venous thrombosis in murine models of ovarian cancer

T Sasano, R Gonzalez‐Delgado, NM Muñoz… - Journal of Thrombosis …, 2022 - Elsevier
Background Podoplanin (PDPN) is a sialylated membrane glycoprotein that binds to C‐type
lectin‐like receptor 2 on platelets resulting in platelet activation. PDPN is expressed on …

Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment

AB Nagaraj, QQ Wang, P Joseph, C Zheng, Y Chen… - Oncogene, 2018 - nature.com
Computation-based drug-repurposing/repositioning approaches can greatly speed up the
traditional drug discovery process. To date, systematic and comprehensive computation …

Crosstalk of immune cells and platelets in an ovarian cancer microenvironment and their prognostic significance

KA Pankowska, GE Będkowska… - International Journal of …, 2023 - mdpi.com
Ovarian cancer (OC) is one of the deadliest gynecological cancers, largely due to the fast
development of metastasis and drug resistance. The immune system is a critical component …

The proteome of clear cell ovarian carcinoma

JX Ji, DR Cochrane, GL Negri… - The Journal of …, 2022 - Wiley Online Library
Clear cell ovarian carcinoma (CCOC) is the second most common subtype of epithelial
ovarian carcinoma. Late‐stage CCOC is not responsive to gold‐standard chemotherapy and …

Incidence and timing of thromboembolic events in patients with ovarian cancer undergoing neoadjuvant chemotherapy

PS Greco, AA Bazzi, K McLean… - Obstetrics & …, 2017 - journals.lww.com
OBJECTIVE: To identify the incidence and timing of venous thromboembolism as well as
any associated risk factors in patients with ovarian, fallopian tube, or primary peritoneal …

Therapeutic strategies focused on cancer-associated hypercoagulation for ovarian clear cell carcinoma

R Tamura, K Yoshihara, T Enomoto - Cancers, 2022 - mdpi.com
Simple Summary Ovarian clear cell carcinoma (OCCC) has a poor prognosis in advanced
cases and displays resistance to standard treatments for epithelial ovarian cancer. OCCC …

Haemostatic Gene Expression in Cancer-Related Immunothrombosis: Contribution for Venous Thromboembolism and Ovarian Tumour Behaviour

V Tavares, J Savva-Bordalo, M Rei, J Liz-Pimenta… - Cancers, 2024 - mdpi.com
Simple Summary The exploration of prognostic biomarkers in ovarian cancer (OC) persists
due to the daunting challenge of therapy resistance and poor patient outcomes …